CLASSIC PRESENTATIONS V

Question 1

severe jaundice in the neonate

Answer 1

crigler najjar syndrome (congenital unconjugated hyperbilirubinemia)

Question 2

golden brown rings around peripheral cornea

Answer 2

wilson disease (kayser-fleischer rings due to copper accumulation)

Question 3

fat, female, forty, fertile

Answer 3

cholelithiasis

Question 4

painless jaundice

Answer 4

cancer of the pancreatic head obstructing bile duct

Question 5

bluish line on gingiva

Answer 5

burton line (lead poisoning)

Question 6

short stature, cafe au lait spots, thumb/radial defects, increase incidence of tumors/leukemia, aplastic anemia

Answer 6

fanconi anemia

Question 7

red/pink urine, fragile RBCs

Answer 7

paroxysmal nocturnal hemoglobinuria

Question 8

painful blue fingers/toes, hemolytic anemia

Answer 8

cold agglutinin disease

Question 9

petechiae, mucosal bleeding, prolonged time

Answer 9

platelet disorders (glanzmann thrombasthenia, bernard soulier)

Question 10

fever, night sweats, weight loss

Answer 10

B symptoms of malignancy

Question 11

skin patches/plaques, pautrier microabcesses, atypical T cells

Answer 11

mycosis fungoides or sezary syndrome (mycosis fungoides+malignant T cells in blood)

Question 12

WBCs that look smudged

Answer 12

CLL

Question 13

neonate with arm paralysis following difficult birth, arm in waiters tip position

Answer 13

Erb Duchenne palsy (C5-C6)

Question 14

anterior drawer sign +

Answer 14

anterior cruciate ligament injury

Question 15

bone pain, bone enlargement, arthritis

Answer 15

osteitis deformans (paget disease of bone, increase osteoblastic and osteoclastic activity)

Question 16

swollen, hard, painful finger joints in an elderly individual, pain worse with activity

Answer 16

osteoarthritis (osteophytes on PIP, bouchard nodes), DIP (heberden nodes)

Question 17

sudden swollen/painful big toe joint, tophi

Answer 17

gout/podagra (hyperuricemia)

Question 18

dry eyes, dry mouth, arthritis in a male

Answer 18

sjrogren syndrome

Question 19

butterfly facial rush and raynauds phenom in a young female

Answer 19

systemic lupus erythematous

Question 20

painful fingers/toes changing color from white to blue to red with cold or stress

Answer 20

raynaud phenom

Question 21

Anticentromere antibodies

Answer 21

scleroderma (CREST)

Question 22

dark purple skin/mouth nodules in a patient with AIDs

Answer 22

kaposi sarcoma, associated with HHV-8

Question 23

anti desmoglein antibodies

Answer 23

pemphigus vulgaris (blistering)

Question 24

pruritic, purple, polygonal planar papules and plaques (6 Ps)

Answer 24

lichen planus

Question 25

increase AFP in amniotic fluid/maternal serum

Answer 25

dating error, ancephaly, spina bifida

Question 26

ataxia, nystagmus, vertigo, dysarthria

Answer 26

cerebellar lesion