CANCER THERAPY II Flashcards
1
Q
MTX, 5-FU, 6-MP, Hydroxyurea
inhibits?
A
nucleotide synthesis
2
Q
alkylating agents, platinum agents, bleomycin, dactinomycin, doxorubicin, etoposide, irinotecan
inhibits?
A
DNA
3
Q
vinca alkaloids and paclitaxel inhibits?
A
cellular division
4
Q
thymidine synthesis
A
MTX
5-FU
5
Q
de novo purine synthesis
A
6-MP
6
Q
inhibits ribonucleotide reductase
A
hydroxyurea
7
Q
cross link DNA
A
alkylating agents, platinum agents
8
Q
DNA stand breakage
A
bleomycin
9
Q
DNA intercalators
A
dactinomycin, doxorubicin
10
Q
inhibits topoisomerase II
A
etoposide/teniposide
11
Q
inhibits topoisomerase I
A
irinotecan/topotecan
12
Q
inhibit microtubule formation
A
vinca alkaloids
13
Q
inhibits microtubule disassembly
A
paclitaxel
14
Q
how does cellular division work again?
A
nucleotide synthesis DNA RNA protein cellular division
