TERATOGENS

Question 1

renal failure, oligohydramnios, hypocalvaria

Answer 1

ACE inhibitors

Question 2

absence of digits, multiple anomalies

Answer 2

alkylating agents

Question 3

ototoxicity

Answer 3

aminoglycosides

Question 4

neural tube defects, cardiac defects, cleft palate, skeletal abnomalities

Answer 4

anti epileptic drugs

Question 5

vaginal clear cell adenocarcinoma, congenital mullerian anomalies

Answer 5

diethylstilbestrol (DES)

Question 6

cartilage damage

Answer 6

fluoroquinolones

Question 7

neural tube defects

Answer 7

folate antagonists

Question 8

multiple severe birth defects

Answer 8

isotretinoin

Question 9

Ebstein anomaly

Answer 9

lithium

Question 10

aplasia cutis congenita

Answer 10

methimazole

Question 11

discolored teeth, inhibited bone growth defects

Answer 11

tetracyclines

Question 12

limb defects

Answer 12

thalidomide

Question 13

bone and cartilage deformities, optic nerve atrophy, fetal cerebral hemorrhage

Answer 13

warfarin

Question 14

fetal alcohol syndrome

Answer 14

alcohol

Question 15

low birth weight, preterm birth, IUGR, placental abruption

Answer 15

cocaine and smoking

Question 16

congenital goiter or hypothyroidism

Answer 16

iodine

Question 17

caudal regression syndrome, cardiac defects, neural tube defects, macrosomnia, neonatal hypoglycemia, polycythemia

Answer 17

maternal diabetes

Question 18

neurotoxicity

Answer 18

methylmercury

Question 19

high risk for spon abortions

Answer 19

vitamin A excess

Question 20

microcephaly, intellectual disability

Answer 20

x-rays