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APMLE PREP > CANCER THERAPY > Flashcards

CANCER THERAPY Flashcards

1
Q

etoposide
teniposide
irinotecan
topotecan

inhibits:
G2 phase-double check repair
S phase-DNA synthesis

A

topoisomerase inhibitors

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2
Q 
azathioprine
cladribrine
cytarabine
5-FU
hydroxyurea
methotrexate
6-mercaptopurine

inhibits:
S phase-DNA synthesis

A

antimetabolites

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3
Q

inhibits G2 phase, double check repair

A

bleomycin

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4
Q

paclitaxel
vinblastine
vincristine

inhibits mitosis

A

microtubule inhibitors

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5
Q 
platinum agents
alkylating agents:
-busulfan
-cyclophosphamide
-ifosfamide
-nitrosureas
A

cell cycle-independent drugs

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APMLE PREP (99 decks)

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