Therapeutic Options Flashcards
Methods to prevent cancer
Environment Diet Screening Genetics Medication/Vaccination
Treatment
Local/regional
Systemic
Local/Regional
Surgery and Radiotherapy
Systemic
Hormonal
Chemotherapy
Whole body irradiation for BMT
4 important biological factors influencing the responses of tumours to radiotherapy
Repair
Reassortment
Repopulation
Reoxygenation
Hormone Therapy
Tamoxifen and ER positive breast cancer
Adjuvant
Surgery follow up
Neo-adjuvant
Shrink tumour before surgery
Immunotherapy
Monocolonal antibodies
Use of PDL-1 on cancer cells and PD1 on T cells: Therapies that target either PD-1 or PD-L1 can stop them from attaching and help keep cancer cells from hiding
Use of PDL-1 and PD1
To treat melanoma and lung cancer
Chimeric antigen receptor (CAR) T cells
- Take blood for patients and separate out T cells
- Disarmed virus is used to produce receptors on T cells (CAR)
- Allow the T cells to recognise and attach to specific proteins or antigen on tumour cells
- T cells are infused into patients
Staging of cancer uses ______
CT, MRI, USS, PET
Pathology and Cytology