An Introduction to Viruses Flashcards
Icosahedral Virus
Rhino virus
Helical
Tobacco Mosaic
Complex
Bacteriophage
Nucleocapsid Envelope
Influenza
Hep C
HIV
Viral Culture
Samples placed with cell type that virus being tested is able to infect and cytopathic effect is observed
Human virus infections of major importance
HIV
Hep B
Hep C
Influenza A and B
Viral Replication
- Attach and uncoat
- Viral contents releaased and enters nucleus
- Viral mRNA used to make viral proteins
- New viral proteins are released
Host Range is _______
An inability of the virus to successfully adsorb or enter cells because of an incompatibility between virus capsid proteins/virus envelope proteins and the host receptor molecule
Consequence of a viral infection
Fever Muscle aches Coughing Headache Chills
Diagnosing Viral Infections
Blood test
Cultures
Spinal Tap (CSF)
PCR
Viral Latency
The ability of a pathogenic virus to lie dormant within a cell (lysogenic)
How do viruses cause cancer
Infections from viruses can cause DNA damage in host and the cells may not be repaired and divide and grow out of control.
Inflammation, direct DNA damage or alteration to immune system
Anti-viral therapy is viral _________
static
Use of antiviral therapy
Prophylaxis
Pre-emptive therapy (before symptoms)
How do you prevent viral infections
Vaccination Passive immunisation Prophylactic Isolation PPE Blood/tissue/organ screening Antenatal screening
