The Small Intestine Flashcards
what is the small bowel
the small intestine
what are the three sections that make up the small intestine
duodenum
jejunum
ileum
what is the small intestine the primary site for in the body
digestion and absorption
where does the small intestine begin
the pylorus
where does the small intestine extend to
the ileocaceal junction
how long is the duodenum
twelve finger lengths, around 25-30cm
why is the jejunum typically empty at post mortem
the result of terminal peristalsis
what does the name jujunum come from
latin for empty and fasting
what is the peritoneum
a continuous membrane lining the abdominal cavity and covers the abdominal viscera
what does the name ileum come from
latin for twisting
what is the parietal peritoneum sensitive to
pressure, pain, temperature
what is the function of the peritoneum
support abdominal organs and provide a route for blood vessels
what does the visceral peritoneum cover
the majority of the abdominal visera.
where does pain from the visceral peritoneum transfer to
dermatomes
what is the serous membrane
two layers continous with each other that are made up of simple squamous epithelial cells called mesothelium
what are intraperitoneal organs enveloped by
visceral peritoneum
what are dermatomes
areas of skin supplied by a single spinal nerve
what does the visceral peritoneum envelope
the intraperitoneual organs
what are the retroperitoneal organs
duodenum, pancreas and rectum
what does the mesentry connect structure to
the posterior abdominal wall
what is the mesentry
a double layer of visceral peritoneum, connecting the structure to the posterior abdominal wall. the mesentry contains blood vessels, nerves and lymphatics.
what does the mesentry contain
blood vessels
nerves
lymphatics
what is the omentum
a sheet of visceral peritoneum extending from the stomach and proximal duodenum to other abdominal organs
where does chyme come from
the stomach
where are brunners glands
above where the pancreatic and biliary secretions enter to duodenum
what do brunners glands secrete
alkaline and mucous secretions
what is the function of brunners glands
to produce alkaline and mucous secretions to protect the duodenum from the acidity of chyme, and provide optimal condition for intestinal enzymes to be active and for lubrication
where is bile stored
the gall bladder
how does bile enter the duodenum of the small intestine
the sphincter of oddi
what does the sphincter of oddi do
controls the flow of bile and the pancreatic juice, or enzymes as they pass into the duodenum
where does the duodenum end
the duodenojejunal junction
what secretions enter the small intestine
bile and pancreatic juice
where is the duodenum found in relation to the vertebrae
sits between L1 and L3/4
what is the shape of the duodenum
C shaped
why is the duodenum C shaped
it comes from the pyloric sphincter through to the duodenojejunal flexure
what does the sphincter of oddi control
the pancreatic and biliary secretions
where is the sphincter of oddi found
the second of the four parts of the duodenum
what is the major duodenal papillae surrounded by
the sphincter of oddi
what is the major duodenal papilla
the rounded projection at the opening of the common bile duct and the pancreatic duct
what is the minor duodenal papilla
the opening of the accessory pancreatic duct - typically present in 10% of people
what does CCK stand for
cholecystokinin
what is CCK
a peptide hormone that helps to digest fat and protein. secreted by cells of the duodenum.
what is CCK secreted by
cells of the duodenum
when is CCK secretion at its highest
when there is fatty acids in the chyme entering the blood stream
what is the function of the CCK hormone
digestion of fat and protein. it also inhibits gastric emptying, but increases the release of pancreatic enzymes, as well as increasing the production of bile.
what does CCK inhibit
gastric emptying
how does CCK result in better fat digestion
increases the release of pancreatic enzymes, as well as increasing the production of bile by contraction of the gall bladder and relaxation of the sphincter of oddi
what are the four parts to the duodenum
- superior
- descending
- inferior
- ascending
what is the superior part to the duodenum
this is the cap and ascends upward from the pyrolus, it is the area that is most common to have a duodenal ulcer. sits at L1
what is the descending section of the duodenum
this passes downward around the head of the pancrea, lying behind the transverse colon, and in front of the right kidney. it is at this site where the major duodenal papilla lies. sits at the level of L1-L3
what is the inferior section of the duodenum
this portion passes to the left over the inferior vena cava and aorta. lies behind the superior mesentric artery, supplying the midgut
what is the ascending section of the duodenum
this crosse the aorta and curves up to join the jejunum at the duodenojejunal flexure
which section of the duodenum is supplied by the gastroduodenal artery
the section prior to the major duodenal papilla in the second part of the duodenum
which section of the duodenum is supplied by the pancreaticoduodenal artery branch of the superior mesentric artery
the section following the major duodenal papillae
what supplies blood to the section of the duodenum prior to the duodenal papilla
the gastroduodenal artery
what supplies blood to the section of the duodenum after the duodenal papilla
the superior mesentric artery and its branch the pancreaticoduodenal artery
why is there venous drainage within the duodenum
to portal the system either through the splenic or superior mesentric vein to the portal vein
give a breakdown on duodenal ulcers
these are breaks in the epithelium, found mostly in the posterior wall of the superior section of the duodenum. the duodenum becomes red, inflammed and ulcerated, where there is damage and disruption to the duodenal epithelium. there is possibility of perforation, and the pain is typically worse at night. thers is upper abdominal pain typically relieved by eating
can lead to air under the diaphragm
what can cause duodenal ulcerations
infections and non steroidal inflammatory drugs like ibuprofen
what could cause sudden intense abdominal pain, fever, nausea and fever
perforation and peritonitis from a duodenal ulcer
what are the treatment options of a perforated duodenal artery that has led to air under the diaphragm
surgery
main function of the duodenum
digestion using pancreatic enzymes and bile
main function of the jejunum
digestion with brush border enzymes and absorption
main function of ileum
absorption
give a breakdown on the layers of the intestine
- lumen
- mucosa
- submucosa
- muscularis externa
- adventitia
what are the layers to mucosa
epithelium, lamina propria, and muscularis mucosae
what are the layers to the muscularis externa
inner circular
outer longitudinal
what are enterocytes in the mucosa
tall columnar epithelium with an absorptive function
what is the function of goblet cells in the small intestine
secrete mucin
what is the function of crypts of lieberkuhn
this is where hormones are secreted and new stem cells are found
what is the function of the submucosa plexus
these are nerves from the parasympathetic nervous system
what is the myenertic plexus responsible for
motor innervation to both layers of muscle. has both parasympathetic and sympathetic innervation
what are plicae circulares
permanent circular folds of mucous membranes which are most numerous in the latter part of the duodenum through the upper part of the jejunum. these increase the surface area in the small intestine.
by how much do villi increase the surface area of the small intestine
10 to 30 times
by how much do microvilli increase the surface area of the small intestine
600 times
how many layers are in the serosa
2 layers of mesothelium
describe the jejunum
located in the upper left quadrant. has a thick intestinal wall, with a longer vasa recta with straight arteries. red in colour
features of the ileum
the lower right quadrant, has a shorter vasa recta, and more arcades. pink in colour. has a thin intestinal wall
which epithelia is present in the intestine
simple columnar
what is the lacteal
a lymphatic vessel that absorbs digested fats
what are peyer’s patches
part of the gut associated lymphoid tissue which is part of the mucosa associated with the lymphoid tissue
what does the circular layer of muscle in the intestine do
local contraction and breakdown
what does the longitudinal layer of muscle in the intestine do
moves bolus further along as well as breaking it down
what is the ileo-caecal junction
a muscular sphincter between the last part of the small intestine and the first part of the large intestine
what is absorbed at the ileo-caecal junction
vitamin B12 and bile acid
what are some clinical notes of the ileum
there are dietary deficiencies. malabsorption syndroms can lead to deficiences that affect blood like anaemia. this can affect the oral mucosa
what are examples of some disorders of the intestinal tract
coeliac disease
crohns disease
cystic fibrosis
what can absorbed through the stomach
caffeine and alcohol
what is the peritoneum wrapped around
the entire abdominal cavity
what is found in between the peritoneum and what is its function
secretions, in order to minimise friction.
what is the purpose of the peritoneum
to hold everything together
where is the parietal peritoneum found
the outside layer of the peritoneum
where is the visceral peritoneum found
looping around organs
what is the omentum a double fold of
mesentry
where does the omentum hang down from
the stomach
what is the function of the omentum
they act as abdominal police. when there is inflammation in the abdomen it starts off as generalised, the omentum then identifies where the inflammation is and wraps around the issue, causing the localised pain and tenderness
where is the mesentry found
around the small intestine
is chyme completely broken down when it reaches the small intestine
no
why does acid from the stomach not harm the lining of the duodenum due to its high pH
the brunners glands at the start of the duodenum neutralise the acid by producing alkaline and mucous secretions
what is the function of bile
aiding fat digestion
what is the function of pancreatic enzymes
digestion of proteins
where does the duodenum sit
close to the pancreas
what is the spleen involved in
processing blood
is the entire duodenum within the abdominal cavity
no, part of it sits behind the peritoneum
what releases CCK
cells in the wall of the duodenum into the bloodstream
what leads to ulcers in the duodenum
repeated irritation
why is the jejunum and the ileum described as infracolic
it is found below the colon
where does the jejunum start
at the duodenumjejunal junction
how long is the small intestine
7 or 8 metres
how long is the large intestine
2 metres
what occurs in the ileum
nutrient absorption
what does the adventitia do
holds everything together
why are there so many nerves innervating the small intestine
to ensure motility happens in a coordinated fashion
can we see villi with the naked eye
no
why do pathologies affect digestion and absorption
because the surface area of the small intestine is so large
describe the blood vessels of the jejunum
longer and not branched
describe the blood vessels of the ileum
shorter and more branched
why are the blood vessels of the ileum more branched than the jejunum
their degree of absorption - there needs to be more blood supply to pick up the nutrients
what do the presence of the submucous glands aid
ensuring everything passes through the small intestine smoothly
where are lacteals found
extending through the middle of the villi
what is peyer’s patch a collection of
lymphoid tissue, or inflammatory tissue
what feature of the ileum is used to differentiate between the ileum and the jejunum
the peyer’s patch
how does intestinal mobility happen
by segmentation; the muscle layers have different functions for breaking down food and passing it down the tract
what is the ileo caecal junction
an opening
what is the function of the apendix
unknown although histological examination of the appendix reveals lymphoid tissue within it.
what can antibiotics change regarding the gut
the gut flora
what can malabsorption symptoms lead to
deficiences that affect blood - anaemia - which can then affect the oral mucosa
what are meckels diverticulum
these are out pouches, and a disease of this is when there are multiple of them. fecal material can build up within them and create an infection. most of the time they are made up of ileal mucosa, but can have epithelium from the stomach, pancreas or the colon, which will irritate it
what are the rules of 2 in related to meckels diverticulum
it occurs in 2% of the population, they are 2 inches long, and are 2 feet away from the ilia-caecal valve.
name all the retroperitoneal organs
- adrenal glands
- aorta and vena cava
- duodenum (descending, inferior and ascending)
- pancreas (not the tail though)
- ureters
- ascending and descending colon
- kidneys
- oesophagus
- rectum