Tetracyclines Flashcards
Are tetracyclines bacteriostatic or bacteriocidal?
Bacteriostatic
What species are tetracyclines normally used for?
Large animal
What is the mechanism of action for tetracyclines?
Bind to bacterial ribosomes and disrupt protien synthesis
What are tetracyclines used to treat in dogs?
Kennel cough
What can happen to a cat who takes an oral tetracycline?
Esophageal stricture
How are tetracyclines best absorbed?
Parenteral or oral administration
What three things interfere with tetracycline absorption?
Dairy products, anti diarrheal agents, antacids
Where are tetracyclines best distributed?
Everywhere but CNS
What is the spectrum of activity for tetracycline 4
G+ G- rickettsia and chlamydia
What are two things tetracyclines can cause in growing animals/fetuses
Yellow discoloration in bones and teeth, and retardation of bone growth
What animals do you not use tetracyclines in?
Animals with impaired kidney function
What can tetracyclines cause in dogs and cats?3
Vomiting, diarrhea, and anorexia
What can doxycycline cause in cats?
Esophageal strictures without water
