Cephalosporins Flashcards
What routes is cephalosporins well absorbed?
Per enteral and oral
What is the mechanism of action for cephalosporins?
Inhibit the formation of the cell wall in actively growing bacteria
What will happen with cephalosporins and the presence of foods?
May or may not effect absorption
Where is cephalosporins well distributed?
All tissues
What body tissues do cephalosporins not reach?
CNS
Where is cephalosporins excreted?
Through kidneys either unchanged or metabolized by the liver
What type of bacteria do cephalosporins attack?
G+
What if cephalosporins ineffective against?
Penicillin resistant bacteria
What are possible allergic reactions to cephalosporins? 5
Shock Skin rash Face swelling Swollen lymph nodes Fever
What can be a side effect of injecting cephalosporins IM?
Pain
What can oral administration of cephalosporins cause?
Vomiting diarrhea anorexia
What type of antibiotics should not be used with cephalosporins?
Bacteriostatic
If overdosed what organ will potentially become toxic?
Kidneys
What type of infection does cephalosporin work better against than penicillin?
Skin infections
