Lincosamides Flashcards
How are lincosamides absorbed?
Parenteral and oral
What is the mechanism of action for lincosamide?
Inhibit bacterial protien synthesis by binding to the ribosomes
How well are lincosamides distributed?
All tissues except the CNS
How are lincosamides eliminated?
Metabolized by the liver and excreted by bial or liver
What is the spectrum of activity for lincosamides?
G+ and Amerindians bacteria
What are two precautions of lincosamides?
Can cause vomiting and diarrhea and don’t use with kaolin (anti diarrheal)
What types of animals are lincosamides used in?
Small animals
What are lincosamides good for?
Bone infections
Is lincosamides bacteriocidal or static?
Both
What animals should lincosamides not be used in?
Pigs, guineapigs, and hamsters