Corticosteroids/glucocorticoids

Question 0

What are two types of corticosteroids?

Answer 0

Mineralocorticoids and glucocorticoids

Question 1

What are corticosteroids?

Answer 1

Hormones produced by the adrenal gland

Question 2

What are minerralocorticoids?

Answer 2

Regulate mineral levels in the body

Question 3

What do glucocorticoids do? 2

Answer 3

Have many effects in the body including antiinflammatory and

Inhibit production of phospholipase

Question 4

How are corticosteroids regulated?

Answer 4

Feedback inhibition

Question 5

What do glucocorticoids affect biologically?

Answer 5

CBC

Question 6

What do glucocorticoids inhibit? 3

Answer 6

Scar tissue formation
T cell formation
Phospholipase production

Question 7

What can glucocorticoids induce?

Answer 7

Labor

Question 8

What can glucocorticoids suppress?

Answer 8

Body’s immune system

Question 9

Of the biologic effects, What can glucocorticoids increase?

Answer 9

Gastric acid secretion
Breakdown of protien
Blood glucose levels

Question 10

What can glucocorticoids decrease? 4

Answer 10

Inflammation
Mucus production in GI
Lymphocytes
Eosinophils

Question 11

What can overuse of glucocorticoids lease to?

Answer 11

Hyperadrenocorticism

Question 12

What are five symptoms of hyperadrenocorticism?

Answer 12

PUPD
Polyphagia 
Alopecia
Muscle atrophy (pot bellied)
Thin skin

Question 13

What are glucocorticoids classified by?

Answer 13

Length of effect

Question 14

What are short acting glucocorticoids?

Answer 14

Biologic effect lasting less than 12 hours

Question 15

What are intermediate acting glucocorticoids?

Answer 15

Biologic effect lastig 12-36 hours

Question 16

What are long acting glucocorticoids?

Answer 16

Last longer that 48 hours

Question 17

What are two examples of short acting glucocorticoids?

Answer 17

Hydrocortisone and cortisone

Question 18

What are five examples of intermediate acting glucocorticoids?

Answer 18

Prednisone
Prednisolone
Triamcinolone
Methylprednisolone
Isoupredone

Question 19

What are three examples of long acting glucocorticoids?

Answer 19

Dexamethasone
Betamethasone
Flumethasone

Question 20

What is an aqueous solution?

Answer 20

The glucocorticoid is combined with a salt and dissolved in water

Question 21

What can be given in large doses intravenously with less risk of an adverse reaction and has a relatively rapid onset of activity?

Answer 21

Aqueous solutions

Question 22

What are two examples of aqueous solutions?

Answer 22

Dexamethasone sodium phosphate

Prednisolone sodium succinate

Question 23

This glucocorticoid formulation does not contain salt and is dissolved in alchohol and the glucocorticoid is the only active ingredient

Answer 23

Alchohol solutions

Question 24

This formulation the glucocorticoid is suspended in a liquid and needs to be shaken

Answer 24

Suspensions

Question 25

How long do suspensions take to absorb?

Answer 25

Period of days

Question 26

What glucocorticoid should never be administer IV and be kept at room temp?

Answer 26

Suspension

Question 27

What are two examples of suspensions?

Answer 27

Methylprednisolone acetate

Triancinone

Question 28

What are six safe guidelines for glucocorticoids

Answer 28

Use another drug if possible
Use smallest dose then reduce
Avoid continuous use, alternate days
Be cautious when using ones that have a long biologic or lasting effect
Taper dose down when discontinuing
Glucocorticoids can be infuriated by other disease processes