Antibiotics and Penicillin Flashcards

0
Q

What was the first widely used antibiotic

A

Penicillin

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1
Q

What are the 9 antibiotic groups

A
Penicillin
Cephalosporin
Amino glycosides
Quinolone a
Tetracycline
Sulfonamides/potential sulfonamide a
Metronidazole
Lincosamides
Chloramphenicol
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2
Q

When was penicillin developed

A

1940s

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3
Q

What antibiotic is the first line of defenses

A

Penicillin

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4
Q

Why do you take food with penicillin

A

Less likely to cause GI upset

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5
Q

Because penicillin is mostly excreted by the kidneys what can this help in dogs and cats?

A

UTI

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6
Q

What is the mechanism of action in penicillin?

A

Interferes with the formation of the cell wall in actively growing bacteria

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7
Q

What routs is pencilling absorbed well?

A

Parent wrap and oral

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8
Q

What penicillin is not well absorbed if given orally?

A

Penicillin G

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9
Q

Which penicillin will not be decreased of food is present

A

Amoxicillin

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10
Q

How well is penicillin distributed?

A

Well to most tissues except eye and CNS

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11
Q

Where is penicillin mostly excreted?

A

Kidneys

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12
Q

What is penicillin mostly effective against?

A

G+

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13
Q

What do resistant G+ bacteria secrete when in contact with penicillin?

A

Beta lactamase

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14
Q

What does beta lactamase effect on penicillin?

A

Disrupts the structure of penicillin molecule

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15
Q

What is penicillin not effective against?

A

G-

16
Q

What are five possible allergic reactions to look for with penicillin?

A

Shock, skin rash, face swelling, swollen lymph nodes, fever

17
Q

What are side effects seen with oral administration?

A

Anorexia, vomiting, diarrhea

18
Q

What species are susceptBle to a penicillin super infection

A

Pigs, hamsters, rabbits

19
Q

I what drugs should you not use with antibiotics?

A

Bacteriostatic a

20
Q

Do you need to watch for withdrawal times with penicillin?

A

Yes