Antibiotics and Penicillin Flashcards
What was the first widely used antibiotic
Penicillin
What are the 9 antibiotic groups
Penicillin Cephalosporin Amino glycosides Quinolone a Tetracycline Sulfonamides/potential sulfonamide a Metronidazole Lincosamides Chloramphenicol
When was penicillin developed
1940s
What antibiotic is the first line of defenses
Penicillin
Why do you take food with penicillin
Less likely to cause GI upset
Because penicillin is mostly excreted by the kidneys what can this help in dogs and cats?
UTI
What is the mechanism of action in penicillin?
Interferes with the formation of the cell wall in actively growing bacteria
What routs is pencilling absorbed well?
Parent wrap and oral
What penicillin is not well absorbed if given orally?
Penicillin G
Which penicillin will not be decreased of food is present
Amoxicillin
How well is penicillin distributed?
Well to most tissues except eye and CNS
Where is penicillin mostly excreted?
Kidneys
What is penicillin mostly effective against?
G+
What do resistant G+ bacteria secrete when in contact with penicillin?
Beta lactamase
What does beta lactamase effect on penicillin?
Disrupts the structure of penicillin molecule