Quinolones Flashcards
What is the mechanism of action for quinolone a?
Disrupt the bacterial DNA molecules
What is the newest antibiotic that is only used on serious infections?
Quinolones
How are quinolones absorbed best?
Oral or parenteral administration
How are quinolones absorbed in mature ruminants orally?
Poor
What happens to quinolones in the presence of food?
Absorbed slowly
How are quinolones distributed?
Penetrate most tissues and at high concentrations except CNS
How are quinolones bio transfused?
Metabolized by liver
How are quinolones excreted?
Bile into intestinal tract and excreted by kidneys
What do quinolones effect?
G-
What animals can suffer articulate cartilage damage from quinolones?
Growing dogs, horses < 3, and pregnant animals
Besides articular damage what else can quinolones cause?
Crystal formation in urine