Chloramphenicol Flashcards
Is chloramphenicol bacteriostatic or Vidal?
Bacteriostatic
What is the mechanism of action for chloramphenicol?
Inhibits bacterial protien synthesis by binding to the ribosomes
How is chloramphenicol best absorbed?
Oral
Where is chloramphenicol distributed?
EVERYWHERE
What is chloramphenicol?
Powerful broad spectrum antibiotic used only occasionally in animals
How is chloramphenicol eliminated?
Metabolized by the liver and excreted by the kidneys
What is the spectrum of activity for chloramphenicol?
G+ g- rickettsia chlamydia and mycoplasma
What animals do you not use chloramphenicol a in?
Animals with impaired liver function or food animals
What can chloramphenicols cause?
Bone marrow suppression in mammals
Why should you take caution with cats and chloramphenicol?
They have a decreased ability to metabolize chloramphenicol
What should you not use chloramphenicol with?
Penicillin or cephalosporins