TEST 7 Flashcards
Cystic fibrosis (CF) is a genetic disorder that primarily affects which body system?
a) Respiratory system
b) Digestive system
c) Cardiovascular system
d) Musculoskeletal system
Respiratory system
Which gene mutation is responsible for causing cystic fibrosis?
a) BRCA1
b) TP53
c) CFTR
d) APOE
CFTR
How is cystic fibrosis inherited?
a) Autosomal dominant
b) Autosomal recessive
c) X-linked recessive
d) Mitochondrial inheritance
Autosomal recessive
Which of the following is a common symptom of cystic fibrosis?
a) Chronic cough
b) Enlarged liver
c) Irregular heartbeat
d) Vision loss
Chronic cough
Cystic fibrosis affects primarily which ethnic group?
a) Asian
b) African
c) Hispanic
d) Caucasian
Caucasian
Cystic fibrosis is caused by a mutation in the ___________________ gene.
CFTR (Cystic Fibrosis Transmembrane Conductance Regulator)
The thick mucus produced in cystic fibrosis can obstruct the ________________ ducts.
Pancreatic
Cystic fibrosis patients often require ________________ supplementation to aid digestion.
Enzyme
The sweat of individuals with cystic fibrosis has a higher concentration of ________________.
Salt (sodium chloride)
The sweat test is a diagnostic method used to measure the levels of ________________ in individuals suspected of having cystic fibrosis.
Chloride
Cystic fibrosis is a curable disease. True or false?
False
Cystic fibrosis affects only the lungs. True or false?
False
All individuals with cystic fibrosis have the same severity of symptoms. True or false?
False
Cystic fibrosis is caused by exposure to environmental toxins. True or false?
False
Cystic fibrosis can be diagnosed prenatally through genetic testing. True or false?
True
What is the average life expectancy of individuals with cystic fibrosis?
a) 30-40 years
b) 50-60 years
c) 70-80 years
d) 90-100 years
50-60 years
Which of the following organs is most commonly affected by cystic fibrosis?
a) Kidneys
b) Lungs
c) Heart
d) Stomach
Lungs
Which type of cystic fibrosis is characterized by milder symptoms and a later onset?
a) Classic CF
b) Atypical CF
c) Late-onset CF
d) Variant CF
Atypical CF
What is the main cause of death in individuals with cystic fibrosis?
a) Respiratory failure
b) Liver failure
c) Kidney failure
d) Heart failure
Respiratory failure
Which of the following is NOT a risk factor for developing cystic fibrosis?
a) Family history of CF
b) Being a carrier of the CF gene
c) Exposure to cigarette smoke
d) Consuming a diet high in sugar
Consuming a diet high in sugar
The first gene associated with cystic fibrosis was identified in ___________.
1989
Cystic fibrosis is caused by the production of thick, sticky ___________.
Mucus
The ___________________ sweat test is the gold standard for diagnosing cystic fibrosis.
Quantitative pilocarpine iontophoresis
The majority of cystic fibrosis cases are diagnosed in ___________.
Childhood
Lung transplantation may be a treatment option for individuals with end-stage ___________ disease.
Pulmonary
How is cystic fibrosis typically diagnosed?
a) Blood test
b) Chest X-ray
c) Lung biopsy
d) Sweat test
Sweat test
Which of the following is NOT a common symptom of cystic fibrosis?
a) Chronic cough
b) Rapid weight gain
c) Bulky stool
d) Salty tasting skin
Rapid weight gain
What is the most common complication associated with cystic fibrosis?
a) Diabetes mellitus
b) Liver cirrhosis
c) Heart disease
d) Lung infections
Lung infections
Which of the following is a preventive measure for cystic fibrosis-related complications?
a) Regular exercise
b) Avoiding dairy products
c) Avoiding close contact with animals
d) Genetic counseling and testing
Genetic counseling and testing
What is the primary goal of cystic fibrosis treatment?
a) Cure the disease
b) Manage symptoms
c) Prevent complications
d) Reverse lung damage
Prevent complications
The thick mucus in cystic fibrosis can lead to ________________.
Lung infections
The gold standard for diagnosing cystic fibrosis is a positive result in the ________________ sweat test.
Chloride
In cystic fibrosis, the pancreas fails to produce enough ________________.
Enzymes
________________ therapy helps to clear mucus from the lungs in individuals with cystic fibrosis.
Chest physiotherapy
Cystic fibrosis affects approximately ________________ in every 2,500 to 3,500 Caucasian births.
1
Cystic fibrosis affects both males and females equally. True or false?
True
Lung transplantation is a potential treatment option for end-stage cystic fibrosis. True or false?
True
Cystic fibrosis is caused by a bacterial infection. True or false?
False
Exercise is not recommended for individuals with cystic fibrosis. True or false?
False
Newborn screening can help detect cystic fibrosis early. True or false?
True
Which of the following organs is commonly affected by cystic fibrosis, leading to digestive problems?
a) Liver
b) Pancreas
c) Kidneys
d) Spleen
Pancreas
What type of therapy involves inhaling a mist of salty water to help clear mucus from the airways?
a) Oxygen therapy
b) Gene therapy
c) Pulmonary rehabilitation
d) Nebulized therapy
Nebulized therapy
Which of the following is a potential complication of cystic fibrosis in males?
a) Infertility
b) Ovarian cysts
c) Uterine fibroids
d) Breast cancer
Infertility
Which of the following medications is commonly used to thin mucus and improve lung function in individuals with cystic fibrosis?
a) Insulin
b) Antibiotics
c) Bronchodilators
d) Corticosteroids
Bronchodilators
What is the average age of diagnosis for cystic fibrosis?
a) Birth
b) 2 years
c) 10 years
d) 18 years
2 years
The most common mutation in cystic fibrosis is known as ________________.
F508del (phenylalanine deletion)
Cystic fibrosis can lead to malnutrition and ________________.
Failure to thrive
The introduction of ________________ in the 1950s significantly improved the survival rates for individuals with cystic fibrosis.
Antibiotics
The median predicted survival age for individuals with cystic fibrosis is currently around ________________ years.
40
All surgeries for cystic fibrosis are very dangerous due to post-operative complications. True or false?
True
Enzymes are a type of:
a) Carbohydrate
b) Protein
c) Lipid
d) Nucleic acid
Protein
Enzymes function as:
a) Catalysts
b) Energy sources
c) Structural components
d) Genetic material
Catalysts
The specific region of an enzyme where a substrate binds is called the:
a) Active site
b) Inactive site
c) Binding site
d) Substrate site
Active site
Enzymes increase the rate of chemical reactions by:
a) Decreasing temperature
b) Increasing pH
c) Lowering activation energy
d) Increasing substrate concentration
Lowering activation energy
Enzymes are highly specific in their catalytic activity due to:
a) Size
b) Shape
c) Charge
d) Temperature
Shape
The lock and key model and the induced fit model are two models used to explain:
a) Enzyme inhibition
b) Enzyme denaturation
c) Enzyme kinetics
d) Enzyme-substrate interaction
Enzyme-substrate interaction
Enzymes are usually named by adding the suffix:
a) “-ase”
b) “-ose”
c) “-ide”
d) “-ine”
“-ase”
Which of the following factors can affect enzyme activity?
a) Temperature
b) pH
c) Substrate concentration
d) All of the above
All of the above
Enzymes are commonly classified into several classes based on their:
a) Size
b) Shape
c) Function
d) Charge
Function
Enzyme activity can be regulated by:
a) Allosteric regulation
b) Competitive inhibition
c) Covalent modification
d) All of the above
All of the above
Enzymes are composed of ________________ chains.
Polypeptide
The ________________ is the substance on which an enzyme acts.
Substrate
Enzymes can be denatured by extreme ________________ and pH.
Temperature
Enzymes are reusable and can catalyze ________________ reactions.
Multiple
Enzymes can be affected by ________________ and non-competitive inhibitors.
Competitive
Enzymes can only catalyze reactions in one direction. True or false?
False
Enzymes are consumed during the catalytic process. True or false?
False
Enzymes function optimally at any pH value. True or false?
False
Enzymes are specific to one type of substrate. True or false?
True
Enzymes can function under extreme temperature conditions. True or false?
False
Enzymes are classified as:
a) Organic compounds
b) Inorganic compounds
c) Macromolecules
d) Small molecules
Macromolecules
The activity of enzymes can be influenced by:
a) Temperature
b) pH
c) Inhibitors
d) All of the above
All of the above
Enzymes work by:
a) Increasing the concentration of reactants
b) Lowering the activation energy
c) Increasing the concentration of products
d) Decreasing the rate of reaction
Lowering the activation energy
Enzymes function best within a specific:
a) pH range
b) Temperature range
c) Pressure range
d) Ionic strength range
pH range
Enzymes can be found in:
a) Animals
b) Plants
c) Microorganisms
d) All of the above
All of the above
Enzymes increase the rate of chemical reactions by lowering the ________________.
Activation energy
The reactant that an enzyme acts upon is known as the ________________.
Substrate
Enzymes can be inhibited by the binding of ________________ to the active site.
Inhibitors
The study of enzymes is known as ________________.
Enzymology
Enzymes are involved in various biological processes such as ________________ and metabolism.
Digestion