TEST 12 Flashcards
The biosynthesis of nucleic acids occurs in the:
a) Cytoplasm
b) Mitochondria
c) Nucleus
d) Golgi apparatus
Nucleus
The building blocks of nucleic acids are called:
a) Amino acids
b) Monosaccharides
c) Nucleotides
d) Fatty acids
Nucleotides
Which enzyme is responsible for the synthesis of RNA from a DNA template?
a) DNA polymerase
b) RNA polymerase
c) Ligase
d) Helicase
RNA polymerase
The process of joining nucleotides to form a new DNA strand is known as:
a) Transcription
b) Translation
c) Replication
d) Translocation
Replication
Which of the following nitrogenous bases is found in RNA but not in DNA?
a) Adenine
b) Thymine
c) Uracil
d) Guanine
Uracil
The synthesis of RNA using a DNA template is called:
a) DNA replication
b) Transcription
c) Translation
d) Reverse transcription
Transcription
The enzyme responsible for adding nucleotides during DNA replication is:
a) DNA polymerase
b) RNA polymerase
c) Ligase
d) Helicase
DNA polymerase
The process by which the genetic information in mRNA is used to build a protein is called:
a) DNA replication
b) Transcription
c) Translation
d) Reverse transcription
Translation
The synthesis of RNA from RNA is called:
a) DNA replication
b) Transcription
c) Translation
d) Reverse transcription
Transcription
The nitrogenous base pairs in DNA are held together by:
a) Covalent bonds
b) Hydrogen bonds
c) Ionic bonds
d) Peptide bonds
Hydrogen bonds
The enzyme responsible for unwinding the DNA double helix during replication is:
a) DNA polymerase
b) RNA polymerase
c) Ligase
d) Helicase
Helicase
Which of the following is not a component of a nucleotide?
a) Phosphate group
b) Sugar
c) Amino group
d) Nitrogenous base
Amino group
The enzyme responsible for joining Okazaki fragments during DNA replication is:
a) DNA polymerase
b) RNA polymerase
c) Ligase
d) Helicase
Ligase
The direction of DNA replication is:
a) 5’ to 3’
b) 3’ to 5’
c) Random
d) Bidirectional
5’ to 3’
Which nucleotide base pairs with adenine in RNA?
a) Thymine
b) Uracil
c) Cytosine
d) Guanine
Uracil
The sugar component in DNA nucleotides is ___________.
deoxyribose
De novo synthesis of purines occurs primarily in the:
a) Nucleus
b) Cytoplasm
c) Endoplasmic reticulum
d) Golgi apparatus
Cytoplasm
The salvage pathway for purine synthesis involves:
a) Synthesizing purines from scratch
b) Recycling purine bases from nucleotide breakdown
c) Breaking down purines into their constituent bases
d) Importing purines from the extracellular environment
Recycling purine bases from nucleotide breakdown
Gout is a form of arthritis caused by the accumulation of:
a) Uric acid
b) Adenosine
c) Guanine
d) Thymine
Uric acid
The enzyme responsible for converting hypoxanthine to xanthine in purine catabolism is:
a) Xanthine oxidase
b) Adenosine deaminase
c) Guanosine kinase
d) Hypoxanthine phosphoribosyltransferase
Xanthine oxidase
SCID (Severe Combined Immunodeficiency) caused by impaired purine salvage pathway is associated with a deficiency in the enzyme:
a) Adenosine deaminase
b) Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
c) Xanthine oxidase
d) Guanosine kinase
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
The accumulation of uric acid crystals in the joints is a characteristic feature of:
a) Gout
b) Leukemia
c) Diabetes mellitus
d) Sickle cell anemia
Gout
The salvage pathway for purine synthesis helps conserve:
a) Energy
b) Nucleotide precursors
c) Enzymes
d) Ribosomes
Nucleotide precursors
In the salvage pathway, the enzyme HGPRT is responsible for:
a) Converting guanine to xanthine
b) Converting adenine to hypoxanthine
c) Converting hypoxanthine to adenosine
d) Converting xanthine to uric acid
Converting adenine to hypoxanthine