Test 2: mycology Flashcards
chemotropic nutrition
passively absorb nutrients from environment
feed on the dead
fungi
fungal cell wall
made mostly of sugar- polysaccharides
ergosterol
why are fungi considered bad antigens
poor immune response because cell wall has little protein- body tends to not see fungi
fungi have polysaccharide and ergosterol cell walls
antifungals attack
ergosterol in fungi cell wall
ergosterol found in other places- can cause side effects
2 forms of fungi
yeast
mold
yeast are —- fungi the reproduce via —
single cell
budding
mold are — fungi that reproduce via —
multicellular
filamentous structures called hyphae
— produce filamentous structures called hyphae
mold
type of fungi
— can switch between yeast and mold based on different environments
dimorphic fungi
— is non infectious and — is infectious in dimorphic fungi
yeast (in animals)
mold (in environment)
how do humans get dimorphic fungi
from the shared environment
not zoonotic
most diagnosis of fungi is by
cytology by a clinical pathologist
cytology= aspirate
a major differential for a fungal infection is —
pyogranulomatous inflammatory disease
fungi culture
can be dangerous for lab personal- send to special lab
takes 28days on special culture
susceptibilty testing very expensive
antigen testing for fungi
can lack specificity- cross reaction with plasmalyte fluids and antimicrobial drugs
antibody testing for fungi
fungi poor antigens- host does not really react
antibody test can be difficult
why is PCR difficult for fungi
cell wall is difficult to disrupt
thrush is caused by
Candida (yeast) (candidiasis)
nosocromial (hospital) infection caused by antimicrobial use
malassezia pachydermatis cause
Dermatitis, otitis and pododermatitis secondary to hypersensitivity is common.
crusty brown nails
pathogenic yeast
— look like gram + snowman or peanut
malassezia pachydermatis
pathogenic yeast- cause dematitis, otitis- crusty nails
malassezia pachydermatis
yeast- cause dermatitis, otitis, crusty nails