Test 2: mycology Flashcards
chemotropic nutrition
passively absorb nutrients from environment
feed on the dead
fungi
fungal cell wall
made mostly of sugar- polysaccharides
ergosterol
why are fungi considered bad antigens
poor immune response because cell wall has little protein- body tends to not see fungi
fungi have polysaccharide and ergosterol cell walls
antifungals attack
ergosterol in fungi cell wall
ergosterol found in other places- can cause side effects
2 forms of fungi
yeast
mold
yeast are —- fungi the reproduce via —
single cell
budding
mold are — fungi that reproduce via —
multicellular
filamentous structures called hyphae
— produce filamentous structures called hyphae
mold
type of fungi
— can switch between yeast and mold based on different environments
dimorphic fungi
— is non infectious and — is infectious in dimorphic fungi
yeast (in animals)
mold (in environment)
how do humans get dimorphic fungi
from the shared environment
not zoonotic
most diagnosis of fungi is by
cytology by a clinical pathologist
cytology= aspirate
a major differential for a fungal infection is —
pyogranulomatous inflammatory disease
fungi culture
can be dangerous for lab personal- send to special lab
takes 28days on special culture
susceptibilty testing very expensive
antigen testing for fungi
can lack specificity- cross reaction with plasmalyte fluids and antimicrobial drugs
antibody testing for fungi
fungi poor antigens- host does not really react
antibody test can be difficult
why is PCR difficult for fungi
cell wall is difficult to disrupt
thrush is caused by
Candida (yeast) (candidiasis)
nosocromial (hospital) infection caused by antimicrobial use
malassezia pachydermatis cause
Dermatitis, otitis and pododermatitis secondary to hypersensitivity is common.
crusty brown nails
pathogenic yeast
— look like gram + snowman or peanut
malassezia pachydermatis
pathogenic yeast- cause dematitis, otitis- crusty nails
malassezia pachydermatis
yeast- cause dermatitis, otitis, crusty nails
— causes nasal cryptococcosis in cats
cryptococcus neoformans
(C. gattii)
true pathogen- yeast- attack neuro and respiratory
cryptococcus neoformans cause —
swelling in face- nasal crypotococcosis in cats and people
C. gattii can also cause this
pathogenic yeast- true pathogen
— is a major neurologic and respiratory pathogen of immunosuppressed people and animals.
cryptococcus neoformans
inhaled from pigeon poop
nasal crytopcoccosis in cats- pathogenic yeast
—- yeast is found in pigeon poop
cryptococcus neoformans
(C. gattii)
nasal swelling in cats
pathogenic yeast
cryptococus neoformans
(C. gattii)
really big capsule!
yeast
the capsule of — is the key antigen for antigen testing
crypotococcus neoformans
(c. gattii)
have very big capsule easy to test for
yeast
two types of mold
hyaline
dematiaceous
hyaline mold produce —-. can cause —- infections
no melanin
opportunistic
Hyalohyphomycosis.
Dematiaceous molds produce —-. Can cause — infections called —
melanin
(rare) but severe
Chromoblastomycosis
what type of mold produces melanin
Dematiaceous molds
(rare) but severe infections collectively called Chromoblastomycosis.
what type of mold produces opportunistic infections
Hyaline molds produce no melanin. Can cause opportunistic infections called Hyalohyphomycosis.
dermatophytes are caused by
hyaline molds (no pigment)
Microsporum (Nannezia), Trychophyton and Epidermaphyton
ringworm is caused by
Dermatophytosis
hyaline mold (no pigment)
Microsporum canis
— is the most common opportunisitic mold
aspergillus
— is a type of mold that effects german shepherds
Systemic aspergillosis
microsporum canis causes —
ringworm in cats
hyaline mold (no pigement)
penicillium is a –
hyaline mold- no pigement
Alternaria is a —
dematiaceous mold
produce melanin
black mold
— is the sugar in the cell wall of aspergillus
galactomannan
mold fungi
— causes rose handlers disease
sporothrix schenkii
dimorphic fungi- spread by contact with infected plants, rare cats to human
sporothrix schenkii cause
lesions along face and limbs
rose handlers disease
spread by dimorphic fungi on plants
rare cats to human
blastomyces dermatiditis is common to
great lakes region and east 1/2 of USA
dimorphic fungi
blastomyces dermatiditis causes
Systemic disease (blastomycosis)- Respiratory and
Cutaneous common
dimorphic fungi
how is blastomyces dermatiditis spread?
environmental soil
replicate in the lungs and then spread through the body in the blood
dimorphic fungi
blastomyces dermatiditis
dimorphic fungi
— is common fungi in the ohio river valley
histoplasma capsulatum
dimorphic fungi
histoplasma capsulatum cause —
Systemic Disease (histoplasmosis): Respiratory, GI lesions
dimorphic fungi, ohio river
— fungi is spread in bird and bat guano
histoplasma capsulatum
dimorphic fungi- ohio river valley
—- causes valley fever
coccidiodes immitis
dimorphic fungi, southwest
coccidiodes immitis cause
valley fever
Systemic Disease (coccidiomycosis):
Primarily respiratory, osteomyelitis,
cutaneous
dimorphic fungi, southwest
how does coccidiodes immitis spread
fungi grow in soil of dry aird regions after a heavy rain
dimorphic fungi, southwest
green- coccidiodes immitis- valley fever
blue- histoplasma capsulatum- bird and bat poop
orange- blastomyces dermatiditis
dimorphic fungi