Teratogens, torches Flashcards
ACE inhibitors
renal damage
Alcohol
FAS (birth defects, mental retardation)
Alkylating agents (2)
Absence of digits
multiple anomalies
Aminoglycosides
CN VIII toxicity
Cocaine (3)
Abnormal fetal development
fetal addiction
placental abruption
Diethylstilbestrol (DES)
Vaginal clear cell adenocarcinoma
Folate antagonists
Neural tube defects
Iodide (lack or excess) (2)
goiter
hypothyroidism
Lithium
Ebstein’s anomaly (atrialized RV)
Maternal diabetes
Caudal regression syndrome (anal atresia to sirenomelia)
Smoking (4)
Preterm labor
Placental problems
IUGR
ADHD
Tetracyclines
Discolored teeth
Thalidomide
flipper limbs
Valproate, carbamazepine
Inhibition of intestinal folate absorption: take 10x normal dose
Warfarin (3)
Bone deformities
fetal hemorrhage
abortion