Autoantibodies Flashcards

1
Q

ANA

A

SLE (also Sjogrens, scleroderma, polymyositis, dermatomyositis, rheumatoid arthritis, juvenile arthritis, MCTD)

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2
Q

Anti-dsDNA, anti-Smith

A

SLE

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3
Q

Antihistone

A

Drug-induced lupus (and SLE)

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4
Q

Anti-IgG

A

Rheumatoid arthritis (anti-IgG is rheumatoid factor)

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5
Q

Anticentromere

A

scleroderma (CREST)

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6
Q

Anti-Scl-70 (anti-DNA topoisomerase I)

A

scleroderma (diffuse)

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7
Q

antimitochondrial

A

primary biliary cirrhosis

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8
Q

Antigliadin, antiendomysial

A

Celiac disease

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9
Q

anti-basement membrane

A

Goodpasture’s

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10
Q

anti-desmoglein

A

Pemphigus vulgaris

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11
Q

Antimicrosomal, antithyroglobulin

A

Hashimoto’s thyroiditis

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12
Q

Anti-Jo-1

A

Sjogren’s syndrome, SLE

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13
Q

Anti-SS-A (anti-Ro)

A

SS, SLE

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14
Q

Anti-SS-B (anti-La)

A

SS, SLE

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15
Q

Anti-U1 RNP (ribonucleoprotein)

A

MCTD

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16
Q

Anti-smooth muscle

A

Autoimmune hepatitis

17
Q

Anti-glutamate decarboxylase

A

DM type I

18
Q

c-ANCA

A

Wegener’s granulomatosis

19
Q

p-ANCA

A

Other vasculitides

20
Q

mpo-ANCA

A

Pauci-immune crescentic glomerulonephritis

21
Q

Anti-TSH

A

Grave’s disease

22
Q

Anti-AcH

A

Myasthenia Gravis