Ovarian Tumors

Question 1

Produces AFP

Answer 1

yolk sac tumor (aka endodermal sinus tumor)

Question 2

Estrogen secreting: leads to precocious puberty

Answer 2

granulosa-theca cell tumor

Question 3

Intraperitoneal accumulation of mucinous material

Answer 3

mucinous cystadenocarcinoma

Question 4

Testosterone secreting, leads to virilization

Answer 4

sertoli-leydig cell tumor

Question 5

Psammoma bodies

Answer 5

serous cystadenocarcinoma

Question 6

Multiple different tissue types

Answer 6

teratoma

Question 7

Lined with fallopian tube-like epithelium

Answer 7

serous cystadenoma

Question 8

Ovarian tumor, ascites, and pleural effusions

Answer 8

Migg’s syndrome of ovarian fibroma

Question 9

Call-Exner bodies

Answer 9

granulosa-theca cell tumor

Question 10

Resembles bladder epithelium

Answer 10

brenner tumor

Question 11

Elevated hCG

Answer 11

choriocarcinoma (sometimes dysgerminoma)

Question 12

An obese woman presents with amenorrhea and increased levels of serum testosterone. What is the diagnosis?

Answer 12

PCOS

Question 13

A patient with polycystic ovarian disease is most at risk for developing what type of cancer?

Answer 13

Endometrial carcinoma

Question 14

Why is progesterone used in combination with estrogen during estrogen replacement therapy?

Answer 14

to reduce risk of endometrial hyperplasia/carcinoma

Question 15

Under what circumstances would you expect to see elevated LH? (4 things)

Answer 15

menopause (with high FSH), PCOS, normally prior to ovulation, androgen insensitivity syndrome

Question 16

What is protective for ovarian cancer?

Answer 16

Breast feeding
Pregnancy
Oral contraceptives
Anything that makes you ovulate less