Bacterial Toxins Flashcards
TSST-1: organism
S. aureus
TSST-1: toxin type
superantigen
TSST-1: effects
toxic shock syndrome: fever, rash, shock
Scarlet fever-erythrogenic toxin: organism
S. pyogenes
Scarlet fever-erythrogenic toxin: effects
toxic shock-like syndrome
Scarlet fever-erythrogenic toxin: toxin type
superantigen
C. diptheria toxin: mechanism
ADP ribosylating A-B toxin: inactivates EF-2
C. diptheria toxin: effects
pharyngitis, pseudomembrane in throat
V. cholerae toxin: mechanism
ADP ribosylating A-B toxin: ribosylation of G protein upregulates adenylyl cyclase
V. cholerae toxin: effects
H2O moves out of cell: rice-water diarrhea
E. coli heat labile toxin: mechanism
ADP ribosylating A-B toxin: stimulates adenylate cyclase
E. coli heat labile toxin: effect
rice-water diarrhea
E. coli heat stable toxin: mechanism
ADP ribosylating A-B toxin simlates guanylate cyclase
E. coli heat stable toxin: effect
Rice water diarrhea
B. pertussis toxin: mechanism
ADP ribosylating A-B toxin: inhibits Galpha1, increases cAMP
B. pertussis toxin: effects
Whooping cough
lymphocytosis
alpha toxin: organism
C. perfringins
alpha toxin: effect
gas gangrene
C. tetani toxin: mechanism
blocks release of GABA and glycine
C. tetani toxin: effect
lockjaw
C. botulinum toxin: mechanism
blocks release of Ach
C. botulinum toxin: effect
anticholinergic symptoms, flaccid paralysis
Edema factor: organism
B. anthracis
Edema factor: mechanism
adenylate cyclase