Renal Diseases Flashcards
Most common nephrotic syndrome in kids
MCD
IF: granular pattern of immune complex deposition
LM: diffuse capillary thickening
Membranous Glomerulonephritis
IF: granular pattern of immune complex deposition
LM: hypercellular glomeruli
Acute PSGN
IF: linear pattern of immune complex deposition
Goodpasture’s syndrome
IF: deposition of IgG, IgM, IgA, and C3 in the mesangium
IgA nephropathy
Kimmelstiel-Wilson lesions (nodular glomerulosclerosis)
Diabetic glomerulonephropathy
Most common nephrotic syndrome in adults
Membranous glomerulonephritis
EM: loss of epithelial foot processes
MCD
Nephrotic syndrome a/w Hep B
Membranoproliferative glomerulonephritis
Nephrotic syndrome a/w HIV
Focal segmental glomerulosclerosis
Anti-GBM antibodies, hematuria, hemoptysis
Goodpasture’s
EM: subendothelial humps and tram-track appearance
Membranoproliferative glomerulonephritis
Nephritis, deafness, cataracts
Alport syndrome
LM: crescent formation in the glomeruli
Rapidly progressive glomerulonephritis
LM: segmental sclerosis and hyalinosis
FSGS