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Autonomic Drugs Flashcards

1
Q

Bethanechol: receptor

A

Muscarinic agonist

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2
Q

Bethanechol: 2 uses

A

Post-operative ileus

Urinary retention

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3
Q

Carbachol: receptor

A

Muscarinic agonist

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4
Q

Carbachol: 2 uses

A

glaucoma

pupillary contraction

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5
Q

Pilocarpine: receptor

A

Muscarinic agonist

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6
Q

Pilocarpine: 2 uses

A

glaucoma, pupillary contraction

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7
Q

Methacholine: receptor

A

muscarinic agonist

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8
Q

Methacholine: use

A

asthma challenge test

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9
Q

Neostigmine: receptor

A

anticholinesterase

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10
Q

Neostigmine: 4 uses

A

post-operative/neurological ileus
urinary retention
Myasthenia Gravis
reversal of NMJ blockade

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11
Q

Pyridostigmine: receptor

A

anticholinesterase

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12
Q

Pyridostigmine: use

A

Myasthenia Gravis

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13
Q

Edrophonium: receptor

A

anticholinesterase

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14
Q

Edrophonium: use

A

diagnosis of myasthenia gravis

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15
Q

Physostigmine: receptor

A

anticholinesterase

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16
Q

Physostigmine: 2 uses

A

glaucoma

atropine overdose

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17
Q

Echothiophate: receptor

A

anticholinesterase

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18
Q

Echothiophate: use

A

glaucoma

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19
Q

Donepezil: receptor

A

anticholinesterase

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20
Q

Donepezil: use

A

Alzheimer’s disease

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21
Q

Galantamine: receptor

A

anticholinesterase

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22
Q

Galantamine: use

A

Alzheimer’s disease

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23
Q

Rivastigmine: receptor

A

anticholinesterase

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24
Q

Rivastigmine: use

A

Alzheimer’s disease

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25
Q

Atropine: receptor

A

muscarinic antagonist

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26
Q

Atropine: 3 uses

A

Insecticide toxicity
dilation of eyes, cycloplegia
decreases secretions during sedation

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27
Q

Homotropine: receptor

A

muscarinic antagonist

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28
Q

Homotropine: use

A

mydriasis

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29
Q

Tropicamide: receptor

A

muscarinic antagonist

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30
Q

Tropicamide: use

A

mydriasis

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31
Q

Pralidoxine: receptor

A

chemical antagonist, regenerates cholinesterase

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32
Q

Pralidoxine: use

A

Insecticide toxicity (use with atropine)

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33
Q

Ipratroprium: receptor

A

muscarinic antagonist

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34
Q

Ipratroprium: use

A

asthma, COPD

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35
Q

Benztropine: receptor

A

muscarinic antagonist

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36
Q

Benztropine: use

A

Parkinson’s

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37
Q

Scopolamine: receptor

A

muscarinic antagonist

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38
Q

Scopolamine: use

A

motion sickness

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39
Q

Oxybutynin: receptor

A

muscarinic antagonist

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40
Q

Oxybutynin: use

A

reduces urgency in mild cystitis, bladder spasms

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41
Q

Glycopyrrolate: receptor

A

muscarinic antagonist

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42
Q

Glycopyrrolate: use

A

decrease airway secretions in surgery

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43
Q

Methscopolamine: receptor

A

muscarinic antagonist

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44
Q

Methscopolamine: use

A

peptic ulcers

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45
Q

Propantheline: receptor

A

muscarinic antagonist

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46
Q

Propantheline: use

A

Peptic ulcers

47
Q

Hexamethonium: receptor

A

Nicotinic receptor ganglionic blocker (para and symp blockade)

48
Q

Hexamethonium: use

A

experimental, prevents vagal reflex to drugs

49
Q

Epinephrine: receptors

A

alpha 1/2

beta 1/2

50
Q

Epinephrine: 4 uses

A

Anaphylactic shock
open angle glaucoma
asthma
hypotension

51
Q

Norepinephrine: receptors

A

alpha 1/2 more than beta 1

52
Q

Norepinephrine: use

A

Septic shock, decreases renal perfusion

53
Q

Isoproterenol: receptors

54
Q

Isoproterenol: use

A

AV block (rarely used)

55
Q

Dopamine: receptors

A

D1/2 more than beta more than alpha

56
Q

Dopamine: 2 uses

A

heart failure, increases renal perfusion

57
Q

Dobutamine: receptors

A

beta 1 more than beta 2

58
Q

Dobutamine: 3 uses

A

cardiogenic shock
heart failure
stress testing

59
Q

Phenylephrine: receptors

A

alpha 1 more than alpha 2

60
Q

Phenylephrine: 3 uses

A

pupillary dilation
vasoconstriction, nasal decongestion
epistaxis

61
Q

Metaproterenol: receptors

A

beta 2 more than beta 1

62
Q

Metaproterenol: use

A

bronchodilation (asthma)

63
Q

Albuterol: receptors

A

beta 2 more than beta 1

64
Q

Albuterol: use

A

acute asthma

65
Q

Levalbuterol: receptors

A

beta 2 more than beta 1

66
Q

Levalbuterol: use

A

acute asthma

67
Q

Salmeterol: receptors

A

beta 2 more than beta 1

68
Q

Salmeterol: use

A

asthma long-term treatment

69
Q

Terbutaline: receptors

A

beta 2 more than beta 1

70
Q

Terbutaline: 2 uses

A

asthma

reduction of premature uterine contractions

71
Q

Ritodrine: receptor

72
Q

Ritodrine: use

A

reduction of premature uterine contractions

73
Q

Amphetamine: mechanism

A

releases stored catecholamines (indirect sympathomimetic)

74
Q

Amphetamine: 4 uses

A

narcolepsy
obesity
ADD
major depressive disorder

75
Q

Ephedrine: mechanism

A

releases stored catecholamines

76
Q

Ephedrine: 3 uses

A

Nasal decongestion
Urinary incontinence
Hypotension

77
Q

Cocaine: mechanism

A

Reuptake inhibitor (NA, dopamine, serotonin)

78
Q

Cocaine: 2 uses

A

Vasoconstriction in nose

Local anesthesia

79
Q

Clonidine: receptor

A

Alpha 2 agonist

80
Q

Clonidine: use

A

renal disease (short acting)

81
Q

Alpha-methyldopa:receptor

A

Alpha 2 agonist

82
Q

Alpha-methyldopa: use

A

renal disease

High BP in pregnancy

83
Q

-olols and -alols: receptor

A

Beta blockers

84
Q

-olols and -alols: 2 uses

A

High BP

comorbidities for heart disease

85
Q

Metroprolol: receptor

A

Beta blocker

86
Q

Metroprolol: use

87
Q

Carbadolol: receptor

A

Beta blocker

88
Q

Carbadolol: use

89
Q

Propranolol: receptor

A

Beta blocker (non-selective)

90
Q

Propranolol: use

A

SVT

thyroid storm

91
Q

Esmolol: receptor

A

Beta blocker (beta 1)

92
Q

Esmolol: use

93
Q

Timolol: receptor

A

Beta blocker (non-selective)

94
Q

Nadolol: receptor

A

Beta blocker (non-selective)

95
Q

Pindolol: receptor

A

Beta blocker (non-selective)

96
Q

Labetalol: receptor

A

Beta blocker (non-selective), alpha blocker

97
Q

Acebutolol: receptor

A

Beta 1 selective blocker

98
Q

Betaxolol: receptor

A

Beta 1 selective blocker

99
Q

Esmolol: receptor

A

Beta 1 selective blocker

100
Q

Atenolol: receptor

A

Beta 1 selective blocker

101
Q

Metrprolol: receptor

A

Beta 1 selective blocker

102
Q

Benefit of Beta 1 selective drugs

A

Less asthma exacerbation

103
Q

Alpha 1 receptor action

A

vasoconstriction (block to dilate)

104
Q

Alpha 2 receptor action

A

vasodilation (block to constrict)

105
Q

Phenoxybenzanine: receptor

A

Non selective alpha blocker

106
Q

Phenoxybenzanine: use

A

Pheochromocytoma (give before beta blocker)

107
Q

Phentolamine: receptor

A

Alpha 1 blocker

108
Q

Phentolamine: use

A

Pheochromocytoma (reversible)

109
Q

-zosins: receptor

A

Alpha 1 blocker

110
Q

-zosins: use

A

Hypertension

Urinary retention in BPH

111
Q

Tamisulisan: receptor

A

Alpha 1 blocker

112
Q

Tamisulisan: use

A

Urinary retention in BPH

113
Q

Mirtazapine: receptor

A

Alpha 2 blocker

114
Q

Mirtazapine: use

A

Depression

Causes sedation and increased appetite

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