G-protein linked 2nd messengers

Question 1

Receptor order

Answer 1

alpha 1
alpha 2
beta 1
beta 2
m1
m2
m3
d1
d2
h1
h2
v1
v2

Question 2

G-protein class order

Answer 2

QISS QIQ SIQ SQS

Question 3

alpha 1: 3 actions

Answer 3

vascular smooth muscle contraction
pupillary dilator muscle contraction (mydriasis)
intestinal and bladder sphincter contraction

Question 4

alpha 2: 2 actions

Answer 4

decreased sympathetic outflow

decreased insulin release

Question 5

beta 1: 4 actions

Answer 5

increased heart rate
increased contractility
increased renin release
increased lipolysis

Question 6

beta 2: 7 actions

Answer 6

vasodilation
bronchodilation
increased HR
increased contractility
increased lipolysis
increased insulin release
decreased uterine tone

Question 7

M1: 2 actions

Answer 7

CNS parasympathetic signal

Enteric nervous system signal

Question 8

M2: 2 actions

Answer 8

decreased HR

decreased contractility of atria

Question 9

M3: 6 actions

Answer 9

increased exocrine secretions
increased peristalsis
increased bladder contraction
bronchoconstriction
miosis
ciliary muscle contraction (accomodation)

Question 10

d1: action

Answer 10

relaxes renal vascular smooth muscle

Question 11

d2: action

Answer 11

modulates transmitter release, especially in brain

Question 12

h1: 4 actions

Answer 12

increased mucus production
bronchiole contraction
pruritus
pain

Question 13

h2: action

Answer 13

increased gastric acid secretion

Question 14

v1:action

Answer 14

vascular smooth muscle contraction

Question 15

v2: action

Answer 15

increased water reabsorption in collecting tubules of kidney