TCR surface molecules Flashcards
1
Q
CD3
A
composed from two subunits epsilon(gamm) and (delta)epsilon
signal transduction
has ITAMs
2
Q
zeta
A
signal transduction, has itams
3
Q
CD28
A
signal transduction
ligand are the B7’s on APCs
4
Q
CTLA-4
A
inhibitory signal receptor/transducer
has ITIMs
ligand are the B7s on APCs
5
Q
PD-1
A
program death 1
inhibitory signal generator
ligand are the PD-L1 and PD-L2
6
Q
LFA-1
A
integrin for adhesion
receptor is ICAM-1
7
Q
CD4/8
A
signal transduction
