Immu innate reactions Flashcards
the two principle types of innate reactions are
inflammatory and antiviral
inflammation–in general–consists in the
accumulation and activation of leukocytes and plasma proteins
kill mostly extracellular microbes and the elimination of damaged tissues
Innate immune defense against intracellular pathogens is mediated by
NK cells. these kill virus infected cells
cytokines called type 1 interferons
microbial molecules that stimulate the innate immune system are called
pathogen associated molecular patterns (PAMPs)
PAMPs are recognized by
pattern recognition receptors (PRRs)
DAMPs
damage-associated molecular patterns
innate immune recognition of molecules released when a cell is damaged