TCA, ETC, OXPHOS

Question 1

PDHC

Answer 1

multi enzyme complex using B1, breaks pyruvate into acetyl coa
(-) acetyl coa, NADH, ATP
(+) NAD, ADP, Ca, pyruvate

Question 2

PDHC deficiency (X linked)

Answer 2

pyruvate shunted to lactate and alanine

Question 3

TCA

Answer 3

Citrate Is Krebs Starting Substrate For Making Oxaloacetate

Question 4

(-) NADH and ATP

Answer 4

PDHC, isocitrate dehydrogenase, alpha KG dehydrogenase

Question 5

Uncoupling Proteins

Answer 5

insert in IMM, creating a pore that ruins proton gradient
increase oxygen consumption but no ATP, just heat

synthetic: aspirin