Fructose And Galactose Metabolism Flashcards
1
Q
Lactose
A
Galactose + glucose
Can be broken into glyceraldehyde (using aldolase) and used in glycolysis or gluconeogenesis
2
Q
Galactose
A
GALT makes UDP glucose for glycogen or G1P to be used in glycolysis or gluconeogenesis
3
Q
Essential fructosuria
A
Defective fructokinase
Benign, get sugar elsewhere
AR
4
Q
Fructose intolerance
A
Deficiency in aldolase b
AR
Build up F1P, increase intracellular phosphate, decrease free phosphate, cause problems (decrease ATP, hypoglycemia, jaundice, increase lactate)
5
Q
Galactose deficiency
A
Deficiency of galactokinase
Galactitol accumulates, mild condition
AR
6
Q
Classic galactosemia
A
No G1P uridyltransferase
AR
Accumulate toxic substances, hepatomegaly, cataracts, intellectual disability
Newborn screener
