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Foundations > PPP > Flashcards

PPP Flashcards

1
Q

Oxidative

A

irreversible
G6P: G6PD: Ribulose5Phosphate
(-) NADPH

to make NADPH

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2
Q

Nonoxidative

A

reversible
Riboluse5Phosphate: trasketolases, B1, transaldolases: ribose5phosphate

to make nucleotides

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3
Q

Tissues for oxidative

A

adipose: FA synthesis
Gonads: steroid
liver: FA
RBC: gluathione reduction (reactive o2)

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4
Q

need NADPH only

A

oxidative = NADPH

nonoxidative to restart cycle

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5
Q

NADPH and ribose5P

A

oxidative

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6
Q

ribose 5P only

A

nonoxidative (high NADPH would inhibit)

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7
Q

NADPH and pyruvate

A

both

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8
Q

G6PD deficieincy (x linked)

A

no NADPH

hemolytic anemia: damage membrane bc Heinz bodies and reactive O2

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Foundations (45 decks)

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