Homocysteine Metabolism Flashcards
1
Q
Methionine Synthase
A
Uses N5methylTHF and B12 to turn homocysteine into methionine (regenerates, not synthesized)
2
Q
SAM
A
Created from methionine, used to donate methyl groups and build nucleotides
Activates cystathione beta synthase (break down HCY)
Inhibit MTHFR and BHMT (prevent HCY to be made into methionine)
3
Q
Hyperhomocysteinemia
A
Problem with MTHFR
Atherosclerosis, stroke, etc