Enzyme Regulation Flashcards
1
Q
Allosteric Regulation
A
modified by noncovalent binding of an effector at a site other than active site, causes confromation changes
positive or negative, homo or heterotropic
2
Q
Covalent modifications
A
phosphorylation, acetylation, ubiquitination
3
Q
mechanisms of regulation
A
substrate availability, product inhibition, allosteric, covalent, synthesis or degradation of enzyme
4
Q
PFK1 and PFBase1 regulation by F26BP
A
low glucose activates FBPase2, decreases F26BP, activates FBPase1 = gluconeogenesis
high glucose activates PFK2, increases F26BP, activates PFK1, = glycolysis
5
Q
Zymogens in digestion
A
trypsinogen and chymotrypsinogen must be activated by peptidases
