SYSTEMS ONC: DERM 1 Flashcards
tumours of skin and subQ are what % in dogs, what in cats?
are tumours of skin and subQ mostly malignant in cats or dogs?
cats
metastatic skin lesions in cats will often be due to which primary neoplasm?
lung-digit syndrome
most skin/subQ tumours rise form which type of tissue?[mesenchymal, epithelial etc]
epithelial
what would be some CONTRAindications for excisional[rather than incisional] biopsy in a skin mass?
basically signs of malignancy!
when should FNA be done on a node?
what is the most common malignant epithelial tumour?
name some (2) more
SCC
canine papilloma are in young dogs are usually benign. however, they can malignantly change into _____
SCC
why does feline SCC often develop is ear tips?
lack of melanin/UV exposure risk
what are the 3 stages/versions in SCC development?
briefly describe them
1 actinic keratosis
2 carcinoma in situ
3 invasive SCC
What is the ideal treatment option for feline SCC?
what are some other tx options?
surgery!
also
* radiotherapy
* photodynamic therapy
* Intralesional chemotherapy
* Electrochemotherapy
* Topical imiquimod
in brady/plesiotherapy, what drug is in the end of the applicator?
strontium 90
briefly describe photodynamic therapy
-early lesions
-systemically give photosensitiser
-then local lihgt source that converts small region into a sensitive form
-good for small tumours
electrochemotherapy
-systemic chemo
-short, high intensity electrical pulses increases cell permeability
-increases drug uptake: more effective
what is a bowenoid carcinoma?
tx of choice?
-SCC in situ (hasnt penetrated basement membrane)
ON MELANNOTIC TUMOURS
benign melanocytoma vs malignant melanoma: benign melanocytoma is usually present where?
hairy skin
whats the difference in tx & prognosis between feline and canine nasal bed tumours?
feline: more radiosensitive, better prognosis
specific sx tx of cutaneous/nailbed melanoma
-removal of all 3 phalanges in digit to ensure adequate sx margin
-sx is difficult
ON SOFT TISSUE SARCOMAS
feline injection site sarcoma (FISS)
-which layer in origin?
-behavior?
-potential latency period length?
what is the 3-2-1 rule in FISS? [it tells you when to be concerned abt a mass]
– any mass present for 3 months or longer
– any mass greater than 2 cm diameter
– any mass that continues to increase in size 1 month after
injection
FISS is usually treated with incisional or excisional biopsy?
incisional
how can surgical clips be used in radiotherapy?
-placed during surgery on tumour margin[deep layer?}
-now shows up during radiology so we know where to place edge border of radiotherapy
[SO in this ex, they have to end up moving the planned tx margin further out]
what are 3 types of round cell cutaneous/SC tumours?
-histiocytic tumours
-mast cell tumours
-lymphoma
???what are 4 types of histioctyic tumours?
describe canine cutaneous histiocytoma:
-breed predisposition?
-lesion appearence?
-diagnostic technique?
lipoma is a tumour of which cells?
benign or malignant?
benign: adipocytes
