NEUROLOGY 8 Flashcards
what is a motor unit? single motor neuron +__________
all the muscle fibers it innervates
ALL suspected peripheral nerve damage patients should have what diagnostics?
what are three types of electrodiagnostic tests for peripheral nerve disease?
-electromyography
-nerve conduction velocity
-repetitive nerve stimulation
[vascular diseases of the peripheral nerve…]
ischaemic neuromyopathy
-signalment?
-signs/history?
signalment
-cats: males mostly
history
-LMN dysfunction, usually in PL
-loss of pain perception
-firm n painful muscles
-cool extremities,
[vascular diseases of the peripheral nerve…]
ischaemic neuromyopathy
-pathogenesis?
path: associated with aortic thromboembolism n cardiomyopathy
[vascular diseases of the peripheral nerve…]
ischaemic neuromyopathy
-diagnosis?
-tx?
-diag: signalment, history, clinical signs
-ultrasound
-elevated CK, AST
-tx: supportive, anti-coag.
[immune/infectious diseases of the peripheral nerve…]
acute polyradiculoneuritis
-history/signs?
-can be due to racoon bite or raw chicken lol
-paresis: initially PL then TL
-reduced reflexes n tone, can affect resp muscles
-WHY RESP IF PL FIRST? NOT DUE TO HPRENIC NEVE?
-
[immune/infectious diseases of the peripheral nerve…]
acute polyradiculoneuritis
-pathogenesis?
-diag?
-tx?
suspected
exclusion
supportive
[normal neuromuscular junction…]
CROSS STUFF OUT/HIGHLIGHT N ADD
acquired myasthenia gravis
-pathogenesis?
-signalment?
-path: serum antibodies formed against nicotinic acetylcholine receptors
-more in dogs
acquired myasthenia gravis
-signs?
-normal before exercise. after:muscle weakness, reduced tone, etc
acquired myasthenia gravis
-diagnosis?
acticholinesterase challenge test
acquired myasthenia gravis
-treatment?
long acting anticholinesterase
masticatory muscle myositis
-history/signs?
-pathogenesis?
-diagnosis/tx?
Protozoal polyradiculoneuritis and myositis
-signs/history?
-pathogenesis?
-acute paraparesis with rigid pelvic limb extension!
-path: toxoplasma gondii or neospora caninum
Protozoal polyradiculoneuritis and myositis
-diagnosis?
-tx?
-diag: detection in serum or biopsies
-tx: anti microbials
botulism
-signalment?
-signs/history?
-dogs
-progressive symmetrical paralysis: PL then TL
-LMN issue
botulism
-pathogenesis?
-tx?
-ingestion of raw food: clostridum botulinum. toxin blocks release of Ach at chollinergic NMJ
-supportive tx
tetanus
-how long after exposure do signs show?
-pathogenesis? which bacteria?
-5-10 days
-clostridium tetani. spores germinate, produce toxin which enters NMJ, goes to CNS. interfere with inhibitory interneurons of spinal cord
tetanus
-tx?
-fl
