ENDOCRINOLOGY 1 Flashcards
between T3 and T4, which is produced more by thyroid gland?
T4
which is the major active thryoid hormone?
T3
T4 in the blood is bound by what? (protien, fat…)
protien
-which helps to regulate bc only unbound thyroid can causes changes to cells
hypothyroidism can be congenital or acquired which is more common?
-can also be primary, seconday, or tertiary. which is most common?
acquired, primary
what is the most common type fo primary acquired hypothyroidism?
primary acquired hypothyroidism:
-signalment?
-breed predisposition?
-breed that is less predisposed?
-sex/status predisposition?
what are the two main categories of clinical signs relating to hypothyroidism?
-metabolic
-dermatological
WHY SO SPECIFIC ABT NOT PUPD LOL
describe the derm signs of hypothyroidism
non-pruritis
bilateral, symmetri flank alopecia
-rat tail
describe changes you might see on haematology, serum biochem, and urinalysis for hypothyroid?
however, hyperlipidaemia could have other differntial diagnosis. name a few.
-post prandial
-secondary due to variety of other conditions
-breed related (schnauzer, shetland, sheltie)
what is the best test for hypothyroidism?
-briefly describe interpretation of results
TT4
-if normal, hypothyroidism is ruled out
-low does not confirm [can be sick euthyroid syndrome or some drugs]
-if high, may be breed related or anti-T4 antibodies
what is sick eurothyroid ?
What are the hormone changes/results of it?
-low TT4 and normal TSH
-sick animals. makes it seem like thyroid funciton is impaired when it rlly isnt
another form of hypothyroid testing is TSH. briefly describe the results
-high=hypothyroid. however, not always
another specific disease testing for hypothyroidism is TgAA. briefly describe the results
50% hypothyroid dogs are positive
ISNT THIS JUST A 50/50 LOL HOW DOES IT HELP
what ratio [low/high] of TT4 to TSH is supportive of a diagnosis of hypothyroidism?
low TT4
increased TSH
describe the tx of hypothyroidism
-drug used?
-what to measure during recheck?
levothyroxine to replace missing hormone
-measure TT4
what are some signs of congenital hypothyroidism?
-proportionate or disproportionate dwarfism?
-disproportionate dwarfism
-failure to thrive
-alopecia-
