ENDOCRINOLOGY 2 Flashcards
hyperthyroidism is due to the elevation of which thyroid hormone?
T4
-also T3 lol
hyperthyroidism signalment?
-breed(s) than is LESS predisposed?
older cats
-pedigree
ON SIGNS
-palpable goiter
one of the most common signs of hyperthyroidism in a clinical exam is palpable goiter.
-describe how to do this technique.
-what causes false positives?
-false negatives?
-DESCRIBE THE TECHNIQUE
-false neg: usually poor technique
-false positive: other structures were palpated
ON TT4 VS FREE T4 FOR DIAGNOSIS:
compare n contrast using TT4 and Free T4 to diagnose hyperthyroidism
the options for hyperthyroidism tx are medical management, dietary management, surgery, and radioactive iodine.
which two of these are curative?
-surgery
-radioactive iodine
ON MEDICAL MANAGEMTN
drugs for medicla management of hyperthyroid inhibit which enzymes?
thyroid peroxidase enzyme
what are some of the most common adverse effects of medical management drugs for hyperthyroid
GI
describe dietary management of hyperthyroidism
low iodine diet
long-term management: dietary , of hyperthyroid:
-advantages?
-disadvantages?
-dis: goiter continues to grow
radioactive I131 long-term management of hyperthyroid:
-advantages?
-disadvantages?
-advantages: >95% cases cured
surgical long-term management of hyperthyroid:
-advantages?
-disadvantages?
-adv: most cases cured
feline primary HYPOthyroidism is very rare. it is often secondary to what?
secondary to tx of hyperthyroid
what si the most common surgical tx of hyperthyroidism?
thyroidectomy
describe the sx technique of a thyroidectomy( AKA modified extracpsular thyroidectomy)
-which muscles are seperated?
-near which tracheal rings?
-
-cat in VD. neck extended. pad on neck
-sternohyoideus muscles
-thyroid is near 2-5th tracheal rings
-seperate parathroid
-remove remainder of thyroid gland
-if you accidentally remove some parathyroid tissue just pop it back in
-wanna leave the parathyroid in there to prevent hypocalcaemia
4 potential surgical complications to thyroidectomy?
-recurrence
-laryngeal paralysis
-hypocalcemia (hypoparathyroidism)
-hypothyroidism
hypothyroidism is often associated with concurrent CKD. why can this be difficult to diagnose
-low muscle mass so low creatinine
-hyperthyroid increases GFR so masks the kidney disease
-instead should run SDMA
Two drug options for medical management of hyperthyroid
Methamizole
Carbimazole (which is metabolized to methamizole)