ENDOCRINOLOGY 5 Flashcards
describe signalment of hypoadrenocorticism
-age?
-sex?
-some breed predispositions?
-usually 2-6 y/o
-F>M
-airedale terrier, basset hound, border terrier
what are some clinical signs of hypoadrenocorticism?
-theyre hella vague and none are pathognomonic!!!
-lethargy
-inappetance/anorexia
-weakness
-PUPD
what could you see on haematology for hypoadrenocorticism?
-no stress leukogram, may be opposite of stress leukogram
-may have non-regen anaemia
what could you see on serum biochem for hypoadrenocorticism?
-azotaemia
-hypercalcaemia
-hyperkalaemia
-hyponatremia
-hypocholesterolaemia
what could you see on urinalysis for hypoadrenocorticism?
-dillute
what is the best specific testing for hypoadrenocorticism?
ACTH stim test
describe tx for acute hypoadrenocorticism
-crystalloid fluid therapy: bolus. to treat hyperkalaemia and hypoglycaemia
-start hormone replacement
what are two possible drugs for hormone replacement in acute hypocorticism?
-dexmathasone
-hydrocortisone CRI
describe tx for chronic hypoadrenocorticism
hormone replacements of glucocorticoids n mineralocorticoids
what is a commonly used drug for glucocorticoid replacement in hypoadrenocorticism?
prednisolone
What are two possible drugs for mineralocorticoids replacemnt in chronic hypoadrenocorticism?
DOCP (L) n fludrocortisone
DOCP should be monitored and levels should be rechecked frequently. during recheck, what levels are you looking at ?
K+ & Na
[because DOCP is a mineralocorticoid, so regulates aldosterone which normally regulated Na and K]
levothyroxine
which condition is this drug used for?
[hypothyroidism, hyperthyroidism, hypoadrenocorticism, hyperadrenocorticism]
hypothyroidism
methamizole
which condition is this drug used for?
[hypothyroidism, hyperthyroidism, hypoadrenocorticism, hyperadrenocorticism]
hyperthyroidism
carbamizole
which condition is this drug used for?
[hypothyroidism, hyperthyroidism, hypoadrenocorticism, hyperadrenocorticism]
hyperthyroidism
dexmethasone
which condition is this drug used for?
[hypothyroidism, hyperthyroidism, hypoadrenocorticism, hyperadrenocorticism]
acute hypoadrenocorticism
hydrocortisone
which condition is this drug used for?
[hypothyroidism, hyperthyroidism, hypoadrenocorticism, hyperadrenocorticism]
acute hypoadrenocorticism
DOCP
which condition is this drug used for?
[hypothyroidism, hyperthyroidism, hypoadrenocorticism, hyperadrenocorticism]
chronic hypoadrenocorticism (its a mineralocorto)
prednisone
which condition is this drug used for?
[hypothyroidism, hyperthyroidism, hypoadrenocorticism, hyperadrenocorticism]
chronic hypeadrenocorticism (its a mienralo)
fludrocortison
which condition is this drug used for?
[hypothyroidism, hyperthyroidism, hypoadrenocorticism, hyperadrenocorticism]
chronic hypoadrenocorticism (its a mineralo)
trilostane
which condition is this drug used for?
[hypothyroidism, hyperthyroidism, hypoadrenocorticism, hyperadrenocorticism]
hyperadrenocortisim
