Special topics 1.7 Immunodeficiencies

Question 1

All antibody isotypes are reduced with Pre B cell differentiation during infancy.

a. Immunodeficiency with hyperimmunoglobulin IgM
b. X-linked agammaglobulinemia
c. DiGeorge anomaly
d. SCID

Answer 1

b

Question 2

Reduced IgA, IgG, IgE with elevated IgM, contains B-cell switching during infancy

a. Immunodeficiency with hyperimmunoglobulin IgM
b. X-linked agammaglobulinemia
c. DiGeorge anomaly
d. SCID

Answer 2

a

Question 3

Deficiency in T cells with some secondary effects on Ab production, Ebryological development of thymus and can be seen in neonatal with hypocalcemia

a. Immunodeficiency with hyperimmunoglobulin IgM
b. X-linked agammaglobulinemia
c. DiGeorge anomaly
d. SCID

Answer 3

c

Question 4

Both T and B cells are deficient with ADA and purine metabolism defect during infancy

a. Immunodeficiency with hyperimmunoglobulin IgM
b. X-linked agammaglobulinemia
c. DiGeorge anomaly
d. SCID

Answer 4

d