10.2 Plasma complement regulators Flashcards

1
Q

Dissociates C1r and C1s from C1q

A

C1 inhibitor (C1-INH)

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2
Q

Cleaves C3b and C4b

A

Factor I

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3
Q

Cofactor with I to inactivate C3b; prevents binding of B to C3b

A

Factor H

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4
Q

Acts as a cofactor with I to Inactivate C4b

A

C4 binding protein (C4BP)

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5
Q

Prevents attachment of the C5b67 complex to cell membrane

A

S protein (Vitronectin)

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