14.1 Properties of Immunoglobulins

Question 1

5 ab classes are base on light or heavy chain?

Answer 1

Heavy

Question 2

Heaviest and the largest molecular weight

a. IgG
b. IgM
c. IgA
d. IgD
e. IgE

Answer 2

b

Question 3

Longest half life in the serum sample

a. IgG
b. IgM
c. IgA
d. IgD
e. IgE

Answer 3

a

Question 4

Smallest molecular weight

a. IgG
b. IgM
c. IgA
d. IgD
e. IgE

Answer 4

a

Question 5

Smallest molecular weight in monomeric form

a. IgG
b. IgM
c. IgA
d. IgD
e. IgE

Answer 5

c

Question 6

The least half life in Ab

a. IgG
b. IgM
c. IgA
d. IgD
e. IgE

Answer 6

d

Question 7

Most abundant Ab in serum

a. IgG
b. IgM
c. IgA
d. IgD
e. IgE

Answer 7

a

Question 8

Least abundant Ab

a. IgG
b. IgM
c. IgA
d. IgD
e. IgE

Answer 8

e

Question 9

Has a constant domain of 4

a. IgG
b. IgM
c. IgA
d. IgD
e. IgE

Answer 9

b and e

Question 10

Has constant domain of 3

a. IgG
b. IgM
c. IgA
d. IgD
e. IgE

Answer 10

a c d

Question 11

Able to activate complement (Complement Fixation)

a. IgG
b. IgM
c. IgA
d. IgD
e. IgE

Answer 11

a and b

Question 12

Most affective in Complement fixation

a. IgG
b. IgM
c. IgA
d. IgD
e. IgE

Answer 12

a

Question 13

Crosses placenta

a. IgG
b. IgM
c. IgA
d. IgD
e. IgE

Answer 13

a

Question 14

IgM can be monomeric which can be seen on the surface of a B cell and pentameric on Serum

T or F

Answer 14

T

Question 15

IgA can be monomer and a Dimer

T or F

Answer 15

T

Question 16

IgD and IgE are only Monomer

T or F

Answer 16

T

Question 17

The most abundant IgG subclass

Answer 17

IgG1

(1,2,3,4)

Question 18

The least abundant IgG subclass

Answer 18

IgG4

Question 19

Subclass of IgG that can cross the placenta

Answer 19

IgG 1,3,4

Question 20

Subclass of IgG that the most effective Complement activator

Answer 20

IgG3

Question 21

Subclass of IgG that is effective in opsonization

Answer 21

IgG1
IgG3

Question 22

IgG4 cant fix complement

T or f

Answer 22

T

Question 23

IgG2 CAN cross the placenta

T or F

Answer 23

F

Cannot

Question 24

An incomplete Ab that provides immunity to newborn and can do opsonization, neutralization of toxins and viruses

a. IgG
b. IgM
c. IgA
d. IgD
e. IgE

Answer 24

a

Question 25

Also known as Mucosal paint a. IgG b. IgM c. IgA d. IgD e. IgE

Answer 25

c

Question 26

Found in the surface of B cell or Marker of Mature B cell Immunoregulator membrane Ig a. IgG b. IgM c. IgA d. IgD e. IgE

Answer 26

d

Question 27

A pentameric a. IgG b. IgM c. IgA d. IgD e. IgE

Answer 27

b

Question 28

Most primitive, agglutination, opsonization and neutralization a. IgG b. IgM c. IgA d. IgD e. IgE

Answer 28

b

Question 29

A Reaginic Ab that is involved in atopic / allergic reaction, parasite and majority of it are attach to mast cells a. IgG b. IgM c. IgA d. IgD e. IgE

Answer 29

e

Question 30

IgE are Heat labile T or F

Answer 30

T

Question 31

Immuno-competent cells have surace receptors that are capable of reaction with antigens, which have complementary side chains to which the specific antigen fit complementarily a. Side chain theory b. Clonal Selection theory

Answer 31

a

Question 32

Who proposed side chain theory?

Answer 32

Ehrlich (1898)

Question 33

Lymphocytes are preprogrammed to produce one type of Ig and a particular cell is capable of responding to it, causing it to proliferate a. Side chain theory b. Clonal Selection theory

Answer 33

b

Question 34

Hybridoma technology is the production of polyclonal antibodies T or F

Answer 34

F Monoclonal

Question 35

In hybridoma technology, Ab is usually produce from what animal

Answer 35

Mices

Question 36

What is being harvested in the mice after Ab-Ag reaction?

Answer 36

Spleen

Question 37

This component fuse Ag-Ab in Hybridoma technology

Answer 37

HGPRT

Question 38

T cell receptor composed of 2 polypeptide chains which are alpha and beta T or F

Answer 38

T

Question 39

Ag specific component: Surface immunoglobulin a. T cell receptor b. B cell receptor

Answer 39

b

Question 40

Ag specific component: Heterodimar alpha-beta / delta, gamma a. T cell receptor b. B cell receptor

Answer 40

a

Question 41

Receptor Valence: Bivalent a. T cell receptor b. B cell receptor

Answer 41

b

Question 42

Receptor Valence: Monovalent a. T cell receptor b. B cell receptor

Answer 42

a

Question 43

Isotype switching a. T cell receptor b. B cell receptor

Answer 43

b