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MTAP 2 Immunology > 17.1 Hypersensitivity reaction > Flashcards

17.1 Hypersensitivity reaction Flashcards

1
Q

Hypersensitivity reactions is a:

Heightened state or immune response

EXAggerated response to a harmful antigen that result to an injury in the tissue, disease, or even death

T or F

A

F

Harmless

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2
Q

NOTE: in remembering the 4 types of hypersensitivity:

ACID (Type 1,2,3,4)

A
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3
Q

What type of hypersensitivity is anaphylactic?

A

Type I

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4
Q

What type of hypersensitivity is Cytotoxic?

A

Type II

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5
Q

What type of hypersensitivity is the Immune complex?

A

Type III

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6
Q

What type of hypersensitivity is Delayed?

A

Type IV

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7
Q

Type I immune mediators?

A

IgE

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8
Q

Type IV immune mediators?

A

T cells

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9
Q

Type III immune mediators?

A

IgG or IgM

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10
Q

Type II immune mediators?

A

IgM and IgG

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11
Q

Antigens involve for this type is heterologous

A

Type I

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12
Q

Antigens involve for this type is Autologous and Heterologous on cell surface

A

Type II

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13
Q

Antigens involve for this type is heterologous and autologous on soluble antigen

A

Type III

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14
Q

Antigens involve for this type is heterologous and autologous

A

Type IV

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15
Q

What type of hypersensitivity involves complement?

A

II and III

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16
Q

Type of hypersensitivity:

Cell destruction by antibody and complement opsonization or ADCC

A

Type II

17
Q

Type of hypersensitivity:

Release of mediators from IgE-sensitized mast cells and basophils

A

Type I

18
Q

Type of hypersensitivity:

Antigen-antibody complexes activate complement proteins

A

Type III

19
Q

Type of hypersensitivity:

Antige-sensitized Th1 cells release cytokine that recruits macrophages and induces inflammation or activates T cells to cause direct cell

A

Type IV

20
Q

Clinical examples for Hypersensitivity:

Contact dermatitis tuberculin, and energy skin tests

A

Type IV

21
Q

Clinical examples for Hypersensitivity:

Transfusion reactions.

A

Type II

22
Q

Clinical examples for Hypersensitivity:

Myasthenia gravis, Goodpasture’s syndrome, Graves disease

A

Type II

23
Q

Clinical examples for Hypersensitivity:

Serum sickness, Arthus reaction

A

Type III

24
Q

Clinical examples for Hypersensitivity:

Lupus erythematosus, rheumatoid arthritis, drug reaction

A

Type III

25
Q

Clinical examples for Hypersensitivity:

Anaphylaxis, allergic rhinitis, allergic asthma

A

Type I

26
Q

Tests for hypersensitivity:

In-Vivo skin test

a. Type I
b. Type II
c. Type III
d. Type IV

A

a

27
Q

Tests for hypersensitivity:

Radioimmunosorbent test and Radioallergosorbent test

a. Type I
b. Type II
c. Type III
d. Type IV

A

a

28
Q

RIST assess allergen Specific IgE

RAST assess Total IgE

T or F

A

F

Blaigtad

29
Q

Tests for hypersensitivity:

Detection of Cold agglutinin

a. Type I
b. Type II
c. Type III
d. Type IV

A

b

30
Q

Tests for hypersensitivity:

Coomb’s test (DAT, IAT)

a. Type I
b. Type II
c. Type III
d. Type IV

A

b

31
Q

DAT detects in vivo sensitization

IAT detects in vitro sensitization

T or F

A

T

32
Q

Tests for hypersensitivity:

Mantoux test (Tuberculin test)

a. Type I
b. Type II
c. Type III
d. Type IV

A

d

33
Q

Tests for hypersensitivity:

Measurement of complement levels

a. Type I
b. Type II
c. Type III
d. Type IV

A

c

34
Q

Tests for hypersensitivity:

Detection of anti-nuclear antibodies

a. Type I
b. Type II
c. Type III
d. Type IV

A

c

35
Q

Tests for hypersensitivity:

Raji Cell Assay

a. Type I
b. Type II
c. Type III
d. Type IV

A

c

MTAP 2 Immunology (41 decks)

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