17.1 Hypersensitivity reaction

Question 1

Hypersensitivity reactions is a:

Heightened state or immune response

EXAggerated response to a harmful antigen that result to an injury in the tissue, disease, or even death

T or F

Answer 1

F

Harmless

Question 2

NOTE: in remembering the 4 types of hypersensitivity:

ACID (Type 1,2,3,4)

Question 3

What type of hypersensitivity is anaphylactic?

Answer 3

Type I

Question 4

What type of hypersensitivity is Cytotoxic?

Answer 4

Type II

Question 5

What type of hypersensitivity is the Immune complex?

Answer 5

Type III

Question 6

What type of hypersensitivity is Delayed?

Answer 6

Type IV

Question 7

Type I immune mediators?

Answer 7

IgE

Question 8

Type IV immune mediators?

Answer 8

T cells

Question 9

Type III immune mediators?

Answer 9

IgG or IgM

Question 10

Type II immune mediators?

Answer 10

IgM and IgG

Question 11

Antigens involve for this type is heterologous

Answer 11

Type I

Question 12

Antigens involve for this type is Autologous and Heterologous on cell surface

Answer 12

Type II

Question 13

Antigens involve for this type is heterologous and autologous on soluble antigen

Answer 13

Type III

Question 14

Antigens involve for this type is heterologous and autologous

Answer 14

Type IV

Question 15

What type of hypersensitivity involves complement?

Answer 15

II and III

Question 16

Type of hypersensitivity:

Cell destruction by antibody and complement opsonization or ADCC

Answer 16

Type II

Question 17

Type of hypersensitivity:

Release of mediators from IgE-sensitized mast cells and basophils

Answer 17

Type I

Question 18

Type of hypersensitivity:

Antigen-antibody complexes activate complement proteins

Answer 18

Type III

Question 19

Type of hypersensitivity:

Antige-sensitized Th1 cells release cytokine that recruits macrophages and induces inflammation or activates T cells to cause direct cell

Answer 19

Type IV

Question 20

Clinical examples for Hypersensitivity:

Contact dermatitis tuberculin, and energy skin tests

Answer 20

Type IV

Question 21

Clinical examples for Hypersensitivity:

Transfusion reactions.

Answer 21

Type II

Question 22

Clinical examples for Hypersensitivity:

Myasthenia gravis, Goodpasture’s syndrome, Graves disease

Answer 22

Type II

Question 23

Clinical examples for Hypersensitivity:

Serum sickness, Arthus reaction

Answer 23

Type III

Question 24

Clinical examples for Hypersensitivity:

Lupus erythematosus, rheumatoid arthritis, drug reaction

Answer 24

Type III

Question 25

Clinical examples for Hypersensitivity: Anaphylaxis, allergic rhinitis, allergic asthma

Answer 25

Type I

Question 26

Tests for hypersensitivity: In-Vivo skin test a. Type I b. Type II c. Type III d. Type IV

Answer 26

a

Question 27

Tests for hypersensitivity: Radioimmunosorbent test and Radioallergosorbent test a. Type I b. Type II c. Type III d. Type IV

Answer 27

a

Question 28

RIST assess allergen Specific IgE RAST assess Total IgE T or F

Answer 28

F Blaigtad

Question 29

Tests for hypersensitivity: Detection of Cold agglutinin a. Type I b. Type II c. Type III d. Type IV

Answer 29

b

Question 30

Tests for hypersensitivity: Coomb's test (DAT, IAT) a. Type I b. Type II c. Type III d. Type IV

Answer 30

b

Question 31

DAT detects in vivo sensitization IAT detects in vitro sensitization T or F

Answer 31

T

Question 32

Tests for hypersensitivity: Mantoux test (Tuberculin test) a. Type I b. Type II c. Type III d. Type IV

Answer 32

d

Question 33

Tests for hypersensitivity: Measurement of complement levels a. Type I b. Type II c. Type III d. Type IV

Answer 33

c

Question 34

Tests for hypersensitivity: Detection of anti-nuclear antibodies a. Type I b. Type II c. Type III d. Type IV

Answer 34

c

Question 35

Tests for hypersensitivity: Raji Cell Assay a. Type I b. Type II c. Type III d. Type IV

Answer 35

c