6.3 Lymphocytes Flashcards
Cells involved in Adaptive IR
Lymphocytes (T and B)
Site of development and maturation for T cells
Thymus
Site of development and maturation for B cells
Bone marrow
Percentage in the blood is 10-15%
B or T cells
B
Percentage in the blood is 75-85%
B or T cells
T cells
Life span is Short for this lymphocyte
T cells
Life span is Long for this lymphocyte
B cells
Lymphocyte subpopulation for T cells
- T helper (CD__)
- T cytotoxic (CD __)
- CD 2
- CD 3
- CD 4
- CD 8
4+
8+
NOTE:
Lymphocyte subpopulation for B cells
- Follicular B cells
- Marginal zone B cells
- B1 cells (Mice)
- Surface Ig
- C Receptors
- MHC Class II
- Mitogen receptors
Which among the Surface marker of B cells is the majority, T dependent and can do class switching
Follicular B cells
Which among the Surface marker of B cells is the edge of Lymphoid follicle
Marginal B cells
Which among the Surface marker of B cells is found in intestinal mucosa and involve in production of natural antibodies
B1 cells
Which among the Surface marker of T cells is the Rosette Marker
CD2
Which among the Surface marker of T cells is the TCR?
CD3
T cells can be identify by Rosette formation with SRBC
T or F
T
B cells can be identify by Surface Ig
T or F
T
Secreted products of T cells
a. Lymphokines
b. Ab
a
Secreted products of B cells
a. Lymphokines
b. Ab
b
Nature of pathogens for T cells:
a. Intracellular microbes
b. Extracellular microbes
a
Nature of pathogens for B cells:
a. Intracellular microbes
b. Extracellular microbes
b
Type of immunity for T cells
Cell mediated
Type of immunity for B cells?
humoral
