6.7 B-cell Development

Question 1

1. Pro B cells
2. Pre B cells
3. Immature B cells
4. Mature B cells
5. Activated B cells
6. Plasma cells
7. Memory B cells

What is the sequence?

Answer 1

1234567

Question 2

CD19+, CD45R
Rearrangement of genes for coding the HEAVY chain

a. Pro B cells
b. Pre B cells
c. Immature B cells
d. Mature B cells

Answer 2

a

Question 3

Presence of mu chain on CYTOPLASM

a. Pro B cells
b. Pre B cells
c. Immature B cells
d. Mature B cells

Answer 3

b

Question 4

Expression of surface IgM, CD 21, CD35

a. Pro B cells
b. Pre B cells
c. Immature B cells
d. Mature B cells

Answer 4

c

Question 5

Rearrangement of genes coding the LIGHT chains

a. Pro B cells
b. Pre B cells
c. Immature B cells
d. Mature B cells

Answer 5

b

Question 6

Expression of both IgM and IgD

a. Pro B cells
b. Pre B cells
c. Immature B cells
d. Mature B cells

Answer 6

d

Question 7

Marginal and Follicular B cells

a. Pro B cells
b. Pre B cells
c. Immature B cells
d. Mature B cells

Answer 7

d

Question 8

CD25-actiaved by Ag

a. Activated B cells
b. Plasma cells
c. Memory B cells

Answer 8

a

Question 9

Class switching, Differentiation

a. Activated B cells
b. Plasma cells
c. Memory B cells

Answer 9

a

Question 10

Activated B cells capable of Ab secretion

a. Activated B cells
b. Plasma cells
c. Memory B cells

Answer 10

b

Question 11

CD27, CD138, CD38

a. Activated B cells
b. Plasma cells
c. Memory B cells

Answer 11

b

Question 12

Contains Hof region (Clear)

a. Activated B cells
b. Plasma cells
c. Memory B cells

Answer 12

b

Question 13

What is the characteristics of nucleus in Plasma cells?

Answer 13

Wagon wheel Appearance

Question 14

This cell has CD25 (-)

a. Activated B cells
b. Plasma cells
c. Memory B cells

Answer 14

b

Question 15

Subtypes of B cells:

B1 has no Ig_ but has CD_

Answer 15

D, 5

Question 16

Subtypes of B cells:

Most, Major responds efectively to T dependent Ag

Answer 16

B2