13.1 Antibodies and TCR

Question 1

Antibodies have Low molecular weight

T or F

Answer 1

F

High

Question 2

Glycoprotein proteins secreted by _______ in response to an antigenic stimulation

Answer 2

Plasma cells

Question 3

Functions of Ab:

Combine with Antigen on cellular surfaces

T or F

Answer 3

T

Question 4

Functions of Ab:

Cannot neutralize toxin substances even by binding to it

T or F

Answer 4

F

Can

Question 5

Functions of Ab:

Can facilitate phagocytosis and opsonin

T or F

Answer 5

T

Question 6

Basic functional unit of Ab?

Answer 6

Monomer

Question 7

how many binding site for a monomer?

Answer 7

2

Question 8

Basic Structural unit of IgG

Answer 8

Monomer

Question 9

Monomer has tetrapeptide meaning

__ Heavy chain

__ Light chain

Answer 9

2

2

Question 10

What region of Antibody is the most flexible part?

Answer 10

Hinge region

Question 11

What chain can hold the antibody together in general?

Answer 11

Disulfide bond

Question 12

Disulfide bond:

Holds Fc and Fab together

a. Interchain
b. Intrachain

Answer 12

a

Question 13

Disulfide bond:

Holds Fab together

a. Interchain
b. Intrachain

Answer 13

b

Question 14

Globular regions of polypeptide chain which stabilized the intrachain disulfide bonds

Answer 14

Domains

Question 15

___________ residue which increases the solubility of the antibody

Answer 15

Carbohydrates

Question 16

Domains on the Variable Regions include VH and VL collectively termed as?

Answer 16

Fab

Question 17

Domains on the constant regions include CL, CH1, CH2 and CH3:

CH1: Bind to ______
CH2: Binding site for C1_
CH3: Attachment to P______________
Fc: Compose of Ch2 and Ch3

Answer 17

C4b
q
Phagocyte

Question 18

Hypervariable Regions are _____ loops

Answer 18

Disecrete

Question 19

Hypervariable regions are found in?

Answer 19

Fab

Question 20

Complementarity-determining regions is the exact or specific areas where the _______ bind

Answer 20

epitopes

Question 21

The area where the epitopes bind is in the CDR and these CDR are found in the?

Answer 21

Fab region

Question 22

Sequence of amino acid comprising polypeptide chain changes

a. Variable region
b. Constant region

Answer 22

a

Question 23

Sequence of amino acid comprising polypeptide chain is fixed and unchanging

a. Variable region
b. Constant region

Answer 23

b

Question 24

Carboxyl group on its terminal end

a. Variable region
b. Constant region

Answer 24

b

Question 25

Amino group (NH2 on its terminal end

a. Variable region
b. Constant region

Answer 25

a

Question 26

Function: binding site for Antigen

a. Variable region
b. Constant region

Answer 26

a

Question 27

Related to the biologic activieites of Ig Molecule

a. Variable region
b. Constant region

Answer 27

b