2.2 Natural / Innate / Native Immunity

Question 1

Intact skin, mucus membrane coated with mucins and ciliated cells

a. External Defense mechanism
b. Internal Defense mechanism

Answer 1

a

Question 2

Ciliated cells do sweeping action to prevent pathogen entering

T or F

Answer 2

T

Question 3

Acidity of the stomach

a. External Defense mechanism
b. Internal Defense mechanism

Answer 3

a

Question 4

Lysozymes inhibits gram (+) bacteria

a. External Defense mechanism
b. Internal Defense mechanism

Answer 4

a

Question 5

Lactic acids in sweat

a. External Defense mechanism
b. Internal Defense mechanism

Answer 5

a

Question 6

Normal Flora

a. External Defense mechanism
b. Internal Defense mechanism

Answer 6

a

Question 7

1st Line of defense

a. External Defense mechanism
b. Internal Defense mechanism

Answer 7

a

Question 8

2nd line of defense

a. External Defense mechanism
b. Internal Defense mechanism

Answer 8

b

Question 9

Cellular and humoral components

a. External Defense mechanism
b. Internal Defense mechanism

Answer 9

b

Question 10

Phagocytic that are known to be frustrated phagocytosis

Answer 10

neutrophils

Question 11

1st innate cells that go to the site

Answer 11

Neutrophils

Question 12

Neutrophils has a long life span

T or F

Answer 12

F

Short

Question 13

Phagocytic that undergo sustained phagocytosis

Answer 13

Monocytes

Question 14

Macrophage:

What organ has Kupffer cells

Answer 14

liver

Question 15

Macrophage:

What organ has Alveolar

Answer 15

lungs

Question 16

Macrophage:

What organ has Microglia

Answer 16

CNS

Question 17

Macrophage:

What organ has Osteoclast

Answer 17

Bone

Question 18

Macrophage:

What organ has Langerhans

Answer 18

Skin

Question 19

Macrophage:

What organ has Histiocytes

Answer 19

CT

Question 20

Macrophage:

What organ has Littoral cells

Answer 20

Spleen

Question 21

Macrophage:

What organ has Mesangial

Answer 21

Kidney

Question 22

Macrophage produces a chemical signal that are involve signaling of other cells

Answer 22

Cytokines

Question 23

Example of Cytokines

Answer 23

IL1, IL2, IFN

Question 24

Macrophage can repair, and clean

T or F

Answer 24

T

Question 25

Macrophage can be adaptive immune response T or F

Answer 25

T

Question 26

Macrophage can be an antigen presentation which is why it can be both innate and adaptive T or F

Answer 26

T

Question 27

Both Neutrophils and Monocytes/Macrophage posses Fc Receptors, and CRP reaction T or F

Answer 27

T

Question 28

Both Neutrophils and Monocytes/Macrophage posses PRRs which is a ____ like receptors

Answer 28

Toll

Question 29

WBC that mediates inflammation

Answer 29

Basophils

Question 30

WBC that mediates Parasite and allegic reaction

Answer 30

Eosinphils

Question 31

This cells is similar function to basophils but no the same

Answer 31

Mast cells

Question 32

WBC that develop in the BM which can be seen in the spleen, liver that share some properties with T Cells

Answer 32

NK cells

Question 33

WBC that is antiviral, anti tumor, and killing via granzymes, and perforins

Answer 33

NK cells

Question 34

Also known as Antibody Dependent Cell Mediated Cytoxicity

Answer 34

NK cells

Question 35

NK cells can cause Indirect killing T or F

Answer 35

F Direct

Question 36

Major (Professional) Antigen presenting cells

Answer 36

Dendritic cells

Question 37

Dendritic cells contains many MHC _ which possess only on antigen presenting cells

Answer 37

2

Question 38

Secretion substances (Humoral) contains antiviral properties, example are C___________, L_________, I_________

Answer 38

Complement Lysozymes Interferons

Question 39

Pattern Recognition Receptors are present in Acquired immune cells (Monocytes / Macrophage) T or F

Answer 39

F Innate

Question 40

Pattern Recognition Receptors recognizes molecular patters that are foreign to the IS such as P____, D_____

Answer 40

PAMPs, DAMPs

Question 41

Toll Like Receptor: ________ - Peptidoglycan (GR__)

Answer 41

TLR2 +

Question 42

Toll Like Receptor: ________ - LPS (Endotoxin)

Answer 42

TLR4

Question 43

Toll Like Receptor: ________ - Lipopeptides of Mycobacteria

Answer 43

TLR1

Question 44

Toll Like Receptor: ________ - dsRNA

Answer 44

TLR3

Question 45

Toll Like Receptor: ________ - ssRNA

Answer 45

TLR7 and 8

Question 46

Toll Like Receptor: ________ - dsDNA

Answer 46

TLR9