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MTAP 2 Immunology > 2.2 Natural / Innate / Native Immunity > Flashcards

2.2 Natural / Innate / Native Immunity Flashcards

1
Q

Intact skin, mucus membrane coated with mucins and ciliated cells

a. External Defense mechanism
b. Internal Defense mechanism

A

a

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2
Q

Ciliated cells do sweeping action to prevent pathogen entering

T or F

A

T

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3
Q

Acidity of the stomach

a. External Defense mechanism
b. Internal Defense mechanism

A

a

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4
Q

Lysozymes inhibits gram (+) bacteria

a. External Defense mechanism
b. Internal Defense mechanism

A

a

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5
Q

Lactic acids in sweat

a. External Defense mechanism
b. Internal Defense mechanism

A

a

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6
Q

Normal Flora

a. External Defense mechanism
b. Internal Defense mechanism

A

a

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7
Q

1st Line of defense

a. External Defense mechanism
b. Internal Defense mechanism

A

a

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8
Q

2nd line of defense

a. External Defense mechanism
b. Internal Defense mechanism

A

b

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9
Q

Cellular and humoral components

a. External Defense mechanism
b. Internal Defense mechanism

A

b

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10
Q

Phagocytic that are known to be frustrated phagocytosis

A

neutrophils

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11
Q

1st innate cells that go to the site

A

Neutrophils

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12
Q

Neutrophils has a long life span

T or F

A

F

Short

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13
Q

Phagocytic that undergo sustained phagocytosis

A

Monocytes

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14
Q

Macrophage:

What organ has Kupffer cells

A

liver

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15
Q

Macrophage:

What organ has Alveolar

A

lungs

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16
Q

Macrophage:

What organ has Microglia

A

CNS

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17
Q

Macrophage:

What organ has Osteoclast

A

Bone

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18
Q

Macrophage:

What organ has Langerhans

A

Skin

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19
Q

Macrophage:

What organ has Histiocytes

A

CT

20
Q

Macrophage:

What organ has Littoral cells

A

Spleen

21
Q

Macrophage:

What organ has Mesangial

A

Kidney

22
Q

Macrophage produces a chemical signal that are involve signaling of other cells

A

Cytokines

23
Q

Example of Cytokines

A

IL1, IL2, IFN

24
Q

Macrophage can repair, and clean

T or F

A

T

25
Q

Macrophage can be adaptive immune response

T or F

A

T

26
Q

Macrophage can be an antigen presentation which is why it can be both innate and adaptive

T or F

A

T

27
Q

Both Neutrophils and Monocytes/Macrophage posses Fc Receptors, and CRP reaction

T or F

A

T

28
Q

Both Neutrophils and Monocytes/Macrophage posses PRRs which is a ____ like receptors

A

Toll

29
Q

WBC that mediates inflammation

A

Basophils

30
Q

WBC that mediates Parasite and allegic reaction

A

Eosinphils

31
Q

This cells is similar function to basophils but no the same

A

Mast cells

32
Q

WBC that develop in the BM which can be seen in the spleen, liver that share some properties with T Cells

A

NK cells

33
Q

WBC that is antiviral, anti tumor, and killing via granzymes, and perforins

A

NK cells

34
Q

Also known as Antibody Dependent Cell Mediated Cytoxicity

A

NK cells

35
Q

NK cells can cause Indirect killing

T or F

A

F

Direct

36
Q

Major (Professional) Antigen presenting cells

A

Dendritic cells

37
Q

Dendritic cells contains many MHC _ which possess only on antigen presenting cells

A

2

38
Q

Secretion substances (Humoral) contains antiviral properties, example are C___________, L_________, I_________

A

Complement

Lysozymes

Interferons

39
Q

Pattern Recognition Receptors are present in Acquired immune cells (Monocytes / Macrophage)

T or F

A

F

Innate

40
Q

Pattern Recognition Receptors

recognizes molecular patters that are foreign to the IS such as P____, D_____

A

PAMPs, DAMPs

41
Q

Toll Like Receptor:

________ - Peptidoglycan (GR__)

A

TLR2

+

42
Q

Toll Like Receptor:

________ - LPS (Endotoxin)

A

TLR4

43
Q

Toll Like Receptor:

________ - Lipopeptides of Mycobacteria

A

TLR1

44
Q

Toll Like Receptor:

________ - dsRNA

A

TLR3

45
Q

Toll Like Receptor:

________ - ssRNA

A

TLR7 and 8

46
Q

Toll Like Receptor:

________ - dsDNA

A

TLR9

MTAP 2 Immunology (41 decks)

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