6.5 T-cell development

Question 1

1. Pro-T/Double negative Thymocytes
2. Mature T cells
3. Sensitized T cells
4. Activated T cells
5. Pre T / Double Positive Thymocytes
6. Prothymocytes

What is the sequence of development?

Answer 1

6,1,5,2,4,3

Question 2

Single positive (After Selection)

a. Prothymocytes
b. Pro-T
c. Pre-T
d. Mature T cells

Answer 2

d

Question 3

Positive and Negative Selection occurs

a. Prothymocytes
b. Pro-T
c. Pre-T
d. Mature T cells

Answer 3

c

Question 4

Thymocyte precursor (Enter the thymus, Cortico medullary junction)

a. Prothymocytes
b. Pro-T
c. Pre-T
d. Mature T cells

Answer 4

a

Question 5

Proliferate in the OUTER CORTEX of THYMUS

a. Prothymocytes
b. Pro-T
c. Pre-T
d. Mature T cells

Answer 5

b

Question 6

CD2, CD5, CD7; CD4___, CD8_____

In PRo T

Answer 6

-,-

Question 7

_______ crucial differentiation and growth

In pro-T

Answer 7

il-7

Question 8

Rearrangement of the genes that code TCR occur Pre-TCR

a. Prothymocytes
b. Pro-T
c. Pre-T
d. Mature T cells

Answer 8

b

Question 9

In Pre-T

CD4__ and CD8____

Answer 9

+ and +

Question 10

Can be CD4 + OR CD 8+

a. Prothymocytes
b. Pro-T
c. Pre-T
d. Mature T cells

Answer 10

d

Question 11

T-cells CD25+

a. Activated T cell
b. Sensitized T cell

Answer 11

a

Question 12

Occurs after encountering the Ag, release of lymphokines

a. Activated T cell
b. Sensitized T cell

Answer 12

b

Question 13

Activation and Recognition of Ag by T cell occurs in ___________ lymphoid organs such as Lymph nodes, and spleen

Answer 13

Secondary