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MTAP 2 Immunology > 9.1 Cytokines and Chemokines > Flashcards

9.1 Cytokines and Chemokines Flashcards

1
Q

Chemical signals, regulates immune system

A

Cytokines

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2
Q

Cytokines are produced by immune cells as well as non-immune cells such as ENDOTHELIAL CELLS

T or F

A

T

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3
Q

Which of the following are pro-inflammatory cytokines?

TNF-alpha
IL1
IL10
IL6
IFN-gamma

A

TNF-alpha
IL1
IL6
IFN-gamma

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4
Q

Which of the following are Major ANTI inflammatory cytokines?

TGF-beta
IFN-Gamma
IL10
IL1
IL13
IL6
IL35

A

TGF-beta
IL10
IL13
IL35

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5
Q

Cytokine associated with innate Immunity:

IL1B
TNF alpha
IL6
TGF-beta
IFN-beta

Which of the following does not belong?

A

None

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6
Q

Cytokine associated with Acquired Immunity:

IL2
IL4
IL5
IL10
IFN-gamma

Which of the following does not belong?

A

None

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7
Q

Cytokine associated with innate Immunity:

Secreted by virally infected cells and increases MHC class I

Activates NK cells

a. IL1B
b. TNF alpha
c. IL6
d. TGF-beta
e. IFN-beta

A

e

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8
Q

Cytokine associated with innate Immunity:

Can induce Fever, inflammation and initiation of the Acute phase response

a. IL1B
b. TNF alpha
c. IL6
d. TGF-beta
e. IFN-beta

A

a

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9
Q

Cytokine associated with innate Immunity:

Associated with death of tumor cells

a. IL13
b. TNF alpha
c. IL6
d. TGF-beta
e. IFN-beta

A

b

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10
Q

Cytokine associated with innate Immunity:

Involves in Activation of CRP and B and T cells

a. IL13
b. TNF alpha
c. IL6
d. TGF-beta
e. IFN-beta

A

c

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11
Q

Cytokine associated with innate Immunity:

Inhinibition of inflammation due to inhibition of T and B cell proliferation, Inhibition of IgA

a. IL13
b. TNF alpha
c. IL6
d. TGF-beta
e. IFN-beta

A

d

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12
Q

Cytokine associated with Acquired Immunity:

Primaly secreted by T cells

a. IL2
b. IL4
c. IL5
d. IL10
e. IFN-gamma

A

All of them

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13
Q

Cytokine associated with Acquired Immunity:

Growth and proliferation of NK, T and B cells

a. IL2
b. IL4
c. IL5
d. IL10
e. IFN-gamma

A

a

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14
Q

Cytokine associated with Acquired Immunity:

Eosinophil generation and activation, B cell differentiation

a. IL2
b. IL4
c. IL5
d. IL10
e. IFN-gamma

A

c

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15
Q

Cytokine associated with Acquired Immunity:

Promotion of Th2 differentiation , IgE class switching

a. IL2
b. IL4
c. IL5
d. IL10
e. IFN-gamma

A

b

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16
Q

Cytokine associated with Acquired Immunity:

Anti-inflammation, suppression of Th2 cells, inhibits interferon-gamma

a. IL2
b. IL4
c. IL5
d. IL10
e. IFN-gamma

A

d

17
Q

Cytokine associated with Acquired Immunity:

Activation of macrophage, increased expression of class I and II MHC molecules

a. IL2
b. IL4
c. IL5
d. IL10
e. IFN-gamma

A

e

18
Q

Promote motility and migration of many WBCs

A

Chemokines

19
Q

Term for the migration of WBC too the infected site

A

Chemotaxis

20
Q

Test to Assess Cytokines:

Enzyme labled immunosorbent spot

a. Elispot
b. ELISA
c. Molecular methods

A

a

21
Q

NOTE:

Test to Assess Cytokines:

Elispot
ELISA
Molecular methods

A

MTAP 2 Immunology (41 decks)

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