Sketchy: Toxoplasmosis Flashcards
1
Q
Cue:
- kitten drinking milk with milk on his head
A
intracranial (brain) calicifications
2
Q
When CD4+ counts are less than 100 and _____ is positive for toxo, give HIV/AIDS pts prophylactic TMP-SMX.
A
IgG
3
Q
Cue:
- Ghandi-looking cat walking with a cane wearing glasses that have extra lens rings and a red turban that has a pin sticking out from it pushing aside a bowl of bubbly-looking meat
A
- Ghandi = Toxoplasma gondii
- cane = immunocompromised (HIV/AIDS)
- multi-ringed glasses = multiple ring enhancing lesions on CT or MRI characteristic of CNS toxo
- red turban = encephalitis
- pin in turban = brain biopsy for dx
- bowl of bubbly-looking meat = cysts in undercooked meat
4
Q
What is the tx for toxo?
A
- sulfadiazine
- pyrimethamine
5
Q
Name a virus that can cause intracranial (brain) calicifications.
A
CMV
6
Q
How can toxo be differentiated from CNS lymphoma?
A
brain biopsy
7
Q
Cue:
- pregnant lady about to take a picture as she changes the litter box filled with poop and eggs, and the camera has a large flash with a weird bulb
A
- pregnant lady = pt population at risk
- litter box = transmitted by cat feces
- eggs = oocysts in the feces
- weird bulb = chorioretinits (congenital toxo or HIV pts)
8
Q
Cue:
- cat dressed as Statue of Liberty
A
T in TORCHES infection
9
Q
How can toxo be transmitted?
A
- consumption of raw/undercooked meat containing cysts
- consumption of water or vegetables contaminated with oocytes from feces of infected animals
- transplacental (a TORCH infection)
10
Q
When CD4+ counts are less than 100 and IgG is positive for toxo, give HIV/AIDS pts prophylactic ______.
A
TMP-SMX
11
Q
Cue:
- kitten with water bowl stuck on his head trying to shake it off
A
- water bowl on head = hydrocephalus
- shaking = seizures
- ** both s/s of congenital toxo
12
Q
Cue:
- cat dressed as Benjamin Franklin with a cane, carrying a $100 bill, standing next to an old Easter egg, flying a kite that has a cross and key on it
A
- Benjamin Franklin = on $100 bill
- $100 bill = CD4+ count less than 100
- cane = immunocompromised
- kite with cross = plus sign = positive
- key = IgG antibody
- old egg = sulfur = TMP-SMX prophylaxis
13
Q
How is toxo diagnosed?
A
- serology (IgG positive)
- biopsy (intramuscular cysts)
14
Q
Toxoplasma gondii is an intracellular, parasitic protozoan that typically infects which patients?
A
- pregnant women
- immunocompromised (HIV/AIDS)
15
Q
____% of the world’s population carries toxo.
A
30%
