Sketchy: Toxoplasmosis Flashcards
Cue:
- kitten drinking milk with milk on his head
intracranial (brain) calicifications
When CD4+ counts are less than 100 and _____ is positive for toxo, give HIV/AIDS pts prophylactic TMP-SMX.
IgG
Cue:
- Ghandi-looking cat walking with a cane wearing glasses that have extra lens rings and a red turban that has a pin sticking out from it pushing aside a bowl of bubbly-looking meat
- Ghandi = Toxoplasma gondii
- cane = immunocompromised (HIV/AIDS)
- multi-ringed glasses = multiple ring enhancing lesions on CT or MRI characteristic of CNS toxo
- red turban = encephalitis
- pin in turban = brain biopsy for dx
- bowl of bubbly-looking meat = cysts in undercooked meat
What is the tx for toxo?
- sulfadiazine
- pyrimethamine
Name a virus that can cause intracranial (brain) calicifications.
CMV
How can toxo be differentiated from CNS lymphoma?
brain biopsy
Cue:
- pregnant lady about to take a picture as she changes the litter box filled with poop and eggs, and the camera has a large flash with a weird bulb
- pregnant lady = pt population at risk
- litter box = transmitted by cat feces
- eggs = oocysts in the feces
- weird bulb = chorioretinits (congenital toxo or HIV pts)
Cue:
- cat dressed as Statue of Liberty
T in TORCHES infection
How can toxo be transmitted?
- consumption of raw/undercooked meat containing cysts
- consumption of water or vegetables contaminated with oocytes from feces of infected animals
- transplacental (a TORCH infection)
When CD4+ counts are less than 100 and IgG is positive for toxo, give HIV/AIDS pts prophylactic ______.
TMP-SMX
Cue:
- kitten with water bowl stuck on his head trying to shake it off
- water bowl on head = hydrocephalus
- shaking = seizures
- ** both s/s of congenital toxo
Cue:
- cat dressed as Benjamin Franklin with a cane, carrying a $100 bill, standing next to an old Easter egg, flying a kite that has a cross and key on it
- Benjamin Franklin = on $100 bill
- $100 bill = CD4+ count less than 100
- cane = immunocompromised
- kite with cross = plus sign = positive
- key = IgG antibody
- old egg = sulfur = TMP-SMX prophylaxis
How is toxo diagnosed?
- serology (IgG positive)
- biopsy (intramuscular cysts)
Toxoplasma gondii is an intracellular, parasitic protozoan that typically infects which patients?
- pregnant women
- immunocompromised (HIV/AIDS)
____% of the world’s population carries toxo.
30%
What is the classic triad in congenital toxo?
- chorioretinitis
- hydrocephalus
- intracranial calcifications
When CD4+ counts are less than _____ and IgG is positive for toxo, give HIV/AIDS pts prophylactic TMP-SMX.
100
In healthy people, toxo may cause _____ but usually it’s asymptomatic.
flu-like symptoms
Cue:
- old dyed Easter eggs with pyramid design on them
- old eggs = sulfur = sulfadiazine
- pyramids = pyrimethamine
Cue:
- cat dressed like Beethoven
deafness in congenital toxo
