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Lindsey's Sketchy Parasites and Fungi > Sketchy: Entamoeba histolytica > Flashcards

Sketchy: Entamoeba histolytica Flashcards

1
Q

What is the tx for Entamoeba histolytica?

A

metronidazole, paramycin, and/or iodoquinol

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2
Q

During the second part of the Entamoeba life cycle, the cysts in the GI tract differentiate into _____.

A

trophozoites

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3
Q

Is surgery of the liver a tx for Entamoeba liver abscesses?

A

NO- treat medically with metro, paramycin, and/or iodoquinol

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4
Q

Cue:

  • bubbles in the puddle
A

cysts

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5
Q

Cue:

  • drainage pipe labeled O&P has outpouchings covered in rust spots and is spilling massive amounts of water
A
  • intestinal amebiasis causes flask-shaped ulcerations of colon haustra with diarrhea
  • stool O&P = diagnostic test
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6
Q

Cue:

  • “Do not enter- Historical site” sign
A
  • Ent = Entamoeba
  • Hist = histolytica
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7
Q

Cue:

  • guy holding a map of the dig site
A

CT of the liver showing R lobe lesion

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8
Q

Entamoeba histolytica trophozoites invade the ____ and spread to the liver via the portal circulation.

A

colon

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9
Q

What is the infectious form of Entamoeba histolytica?

A

the cysts

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10
Q

Cue:

  • pair of mice running out of the metro tunnel
A

paramycin, a luminal agent used to eliminate cysts

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11
Q

How is Entamoeba histolytica diagnosed?

A
  • stool O&P positive for cysts or trophozoites
  • ELISA antigen test on stool and serum
  • serology to test for entamoeba antibody
  • biopsy shows Erlenmeyer flask ulcerations during C-scope
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12
Q

How does Entamoeba histolytica look on microscopy?

A

trophozoites containing endocytosed RBCs

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13
Q

Is Entamoeba histolytica invasive?

A

YES - it causes colon ulcers, bloody diarrhea (dysentery)

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14
Q

Cue:

  • 2 men holding hands and drinking the dirty, bubbly puddle water from Erlenmeyer flasks
A
  • transmission = ingestion of cysts from contaminated water
  • also assoc with men who have sex with men (anal-oral transmission)
  • Erlenmeyer flasks = shape of ulcers in colon
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15
Q

What is paramycin?

A

a luminal agent used to eliminate cysts (tx for Entamoeba histolytica)

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16
Q

Cue:

  • archeologists digging for a tomb on the R side of the liver-shaped dig site
A

R lobe of liver is most common involved site of amoebic liver abscesses

17
Q

Cue:

  • a metro subway train
A

metronidazole

18
Q

What is Iodoquinol?

A

a luminal agent used to eliminate cysts (tx for Entamoeba histolytica)

19
Q

What drugs work by eliminating cysts from the lumen of the intestine?

A

luminal agents:

  • paramycin
  • iodoquinol
20
Q

Cue:

  • anchovy paste truck driving by and an archaeologist eating a dripping sandwich while sitting on a red stool
A
  • “anchovy paste” pus consistency of amoebic liver abscesses
  • red stool = bloody diarrhea
21
Q

What is the classic description for the pus inside an amoebic liver abscess?

A

anchovy paste

22
Q

The _____ of the liver is most common involved site of amoebic liver abscesses.

A

right lobe

23
Q

Cue:

  • sign says “Queen Iodo’s Tomb”
A

Iodoquinol, a luminal agent used to eliminate cysts

24
Q

Cue:

  • amoeba-shaped puddle with floating red cups
A

trophozoites contain endocytosed RBCs

25
Q

Cue:

  • shape of the dig site
A

liver (trophozoites spread from GI tract to liver via portal circulation)

26
Q

Are most amoebic liver abscesses solitary or multiple lesions?

A

solitary (70-80%)

27
Q

Entamoeba histolytica causes what disease?

A

amoebiasis

28
Q

What are the s/s of amoebic liver abscesses?

A
  • RUQ pain
  • hepatomegaly
  • TTP
29
Q

Cue:

  • man standing in the R sided digging site holding his upper abdomen
A

RUQ pain in amoebic liver abscesses

30
Q

What is dysentery?

A

bloody diarrhea

31
Q

Entamoeba histolytica trophozoites invade the colon and spread to the _____ via the ______.

A

liver; portal circulation

32
Q

_______ invade the colon and spread to the liver via the portal circulation.

A

Entamoeba histolytica trophozoites

33
Q

What are the 2 life cycle stages for Entamoeba histolytica?

A
  1. cysts
  2. trophozoites

Lindsey's Sketchy Parasites and Fungi (32 decks)

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