Sketchy: Blastomycosis dermatididis Flashcards
1
Q
What is the geographical buzzword for Blasto?
A
- Great Lakes
- Ohio River Valley
2
Q
Cue:
- butterfly
A
- dimorphism (mold in the cold soil, yeast in the heat body)
3
Q
How big is Blastomycosis dermatididis compared to an RBC?
A
about the same size
4
Q
How does PNA from Blastomycosis dermatididis look on CXR?
A
- patchy, alveolar infiltrate (hazy)
- lesions or cavitations
5
Q
How is Blastomycosis dermatididis treated?
A
- -conazoles for mild/local infection
- Amphotericin B = severe/systemic
6
Q
Cue:
- soldier, surrounded by pine cones, coughing as he inhales the cannon smoke and holds 2 cannon balls that are stuck together
A
- pine cones = -conazoles = tx for local/mild infection
- smoke = aerosolized fungus –> transmission
- coughing = inhaled (transmission)
- double cannon ball = broad-based budding
7
Q
How do the majority of Blastomycosis dermatididis infections present?
A
they’re subclinical or asymptomatic
8
Q
Cue:
- cracked, dry valley where cannonballs are landing, so it looks hazy
A
- cracks = lobes of the lungs (3 on right, 2 on left)
- cannonball craters = lesions/cavities
- haze = patchy, alveolar infiltrate on CXR
9
Q
How is Blastomycosis dermatididis diagnosed?
A
- KOH prep –> round yeast with single, broad-based bud
- culture
- urine antigen test
10
Q
Cue:
- in a valley along a yellow river
A
- location of Blastomycosis dermatididis = Ohio river valley
- yellow river = detect with urine antigen test
11
Q
Once in the lungs, Blastomycosis dermatididis replicates by _____.
A
broad-based budding
12
Q
Cue:
- statue of Robert E. Lee carrying a cane, but chunks are missing out of it and there are ulcerating craters and a bone sticking out, and it’s surrounded by frogs
A
- Blastomycosis dermatididis occurs in the southern US
- craters etc = disseminated infection to skin and bone
- frogs = amphibians = amphotericin B = tx for severe case
