Sketchy: Paracoccidioides brasiliensis Flashcards

1
Q

What is the tx for Paracoccidioides brasiliensis?

A
  • -conazole for mild infection
  • Amphotericin B for systemic
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2
Q

How does Paracoccidioides brasiliensis look in its yeast form?

A

like a captain’s wheel - multiple buds radiate out from a central vacuole

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3
Q

How big is Paracoccidioides brasiliensis compared to an RBC?

A

MUCH bigger

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4
Q

Cue:

  • a Captain’s wheel with round, bulb-shaped handles and red center
A
  • yeast form looks like a captain’s wheel - multiple buds radiate out from a central vacuole
  • red center = RBC, so Paracoccidioides brasiliensis is MUCH bigger than an RBC
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5
Q

Where is Paracoccidioides brasiliensis found?

A

in Brazil and South America

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6
Q

Cue:

  • pinecones and frogs
A
  • -conazole for mild infection
  • Amphotericin B for systemic
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7
Q

Cue:

  • butterfly tattoo
A

dimorphic (mold in the cold, yeast in the heat)

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8
Q

Cue:

  • pirate, who has white beads in his hair and is wearing a medallion necklace, is coughing and showing his yucky mouth
A
  • cough = respiratory transmission and causes cough
  • beads = cervical lymphadenopathy
  • necklace = lung granulomas
  • mouth = mucocutaneous ulcers and lesions
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9
Q

What happens when Paracoccidioides brasiliensis disseminates?

A

causes cervical, axillary, or inguinal adenopathy –> lungs –> granulomas

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10
Q

Cue:

  • treasure map of South America
A

found in Brazil and South America

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